Publications by authors named "Elisabeth S Yan"
Background: The majority of neonatal NIRS literature recommends target ranges for cerebral saturation (rScO) based on data using adult sensors. Neonatal sensors are now commonly used in the neonatal intensive care unit (NICU). However, there is limited clinical data correlating these two measurements of cerebral oxygenation.
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- - The study evaluates multi-organ dysfunction (MOD) in newborns receiving therapeutic hypothermia (TH) for hypoxic ischemic encephalopathy (HIE), focusing on comparing outcomes based on MRI findings.
- - In a retrospective analysis of 157 infants, 77% experienced dysfunction in two or more organ systems, with hematologic and hepatic issues being the most common.
- - A strong link was found between the number of dysfunctional organ systems and negative outcomes such as death or severe brain injury, indicating that MOD could significantly influence clinical care and parental counseling.
Objective: Many critically ill neonates have an existing brain injury or are at risk of neurologic injury. We developed a "NeuroNICU" (neurologic neonatal intensive care unit) to better provide neurologically focused intensive care.
Study Design: Demographic and clinical variables, services delivered, and patient outcomes were recorded in a prospective database for all neonates admitted to the NeuroNICU between April 23, 2013, and June 25, 2015.