Publications by authors named "Elisabeth Muyamuna"
Incidence of human monkeypox (mpox) has been increasing in West and Central Africa, including in the Democratic Republic of Congo (DRC), where monkeypox virus (MPXV) is endemic. Most estimates of the pathogen's transmissibility in the DRC are based on data from the 1980s. Amid the global 2022 mpox outbreak, new estimates are needed to characterize the virus' epidemic potential and inform outbreak control strategies.
View Article and Find Full Text PDFThe current worldwide monkepox outbreak has reaffirmed the continued threat monkeypox virus (MPXV) poses to public health. JYNNEOS, a Modified Vaccinia Ankara (MVA)-based live, non-replicating vaccine, was recently approved for monkeypox prevention for adults at high risk of MPXV infection in the United States. Although the safety and immunogenicity of JYNNEOS have been examined previously, the clinical cohorts studied largely derive from regions where MPXV does not typically circulate.
View Article and Find Full Text PDFArticle Synopsis
- Monkeypox is an emerging disease primarily seen in Central and Western Africa, and this study analyzed cases in Tshuapa Province, Democratic Republic of the Congo, from 2011 to 2015.
- Out of 1057 confirmed cases, the annual incidence was 14.1 per 100,000, with higher rates in males, particularly those aged 10-19, who showed the most animal exposures.
- The research indicates that monkeypox incidence has doubled since the 1980s, potentially due to reduced immunity from smallpox vaccinations, highlighting demographic variations in exposure patterns related to cultural practices.