Publications by authors named "Elisabeth Marcotullio"
Article Synopsis
- Ovarian cancer is rare but has a poor prognosis, with hormones and reproductive factors potentially linking it to endocrine disruptors in agricultural settings.
- In a study involving 59,391 female farmers, the impact of specific agricultural exposures during different life stages on ovarian cancer risk was analyzed, revealing both increased and decreased risks associated with various farming activities.
- Key findings indicated that involvement with pigs, fruit-growing, and potato seed treatment elevated ovarian cancer risk, particularly during puberty, while grain cereal farming showed a reduced risk; exposure to triazine herbicides was not linked to increased ovarian cancer.
Sarcomas are a heterogeneous group of tumors whose incidence is nearly 5 per 100 000 inhabitants in Europe. Their causes are poorly understood, although occupational exposures (especially farming and pesticides) are suspected. The AGRICAN cohort is a prospective study of 181 842 individuals enrolled in 2005 to 2007 who completed an enrolment questionnaire with data on lifelong agricultural exposure.
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- The study aimed to explore the relationship between time-to-pregnancy (TTP) and exposure to agricultural work and pesticides among women in the AGRICAN cohort.
- Data was collected from 616 women who reported pregnancies between 2005 and 2017, analyzing their farming activities and conditions prior to conception.
- Results indicated a non-significant decrease in fecundability linked to farm work, night shifts, and exposure to vibrations, suggesting that these factors may contribute to a longer time-to-pregnancy.
Purpose: Epidemiological studies have found an increased risk of multiple myeloma (MM) in farmers. Few studies have investigated the detailed circumstances of occupational pesticide exposure which could explain these increased risks (pesticide use on crops, seeds or on animals, contact with treated crops) and the role of other exposures. In the Agriculture and Cancer cohort (AGRICAN), we assessed the associations between MM and crop- or animal-related activities, with specific attention to pesticide exposure via use on animals and crops or contact with treated crops and to disinfectant exposure.
View Article and Find Full Text PDFObjectives: Farmers are considered at lower risk of lung cancer. However, specific tasks can expose them to hazardous air contaminants such as pesticides, diesel exhaust and mineral dust. This study aimed to assess the associations between various crops and related tasks and the risk of lung cancer, overall and by histological subtypes.
View Article and Find Full Text PDFBackground And Aim: Epidemiological studies have reported an increased risk of Parkinson's disease (PD) in farmers exposed to pesticides, but no clear conclusion can be drawn on the type of pesticide and duration of use associated with an effect. In the French agricultural cohort AGRICAN, we assessed associations between PD and pesticide use according to the types of livestock and crops grown, including exposure to some active ingredients with duration of use.
Methods: Self-reported PD and history of lifetime exposure to 13 crops and 5 types of animals and pesticide use were collected at enrolment (2005-07) among 181 842 participants.
Epidemiologic studies have found lower risks of lung cancer in farmers. However, little is known about the types of agricultural activities concerned. In the Agriculture and Cancer cohort, we assessed the relationship between animal farming and lung cancer by investigating the types of animals, tasks, and timing of exposure.
View Article and Find Full Text PDFBackground: Numerous studies have been conducted among farmers, but very few of them have involved large prospective cohorts, and few have included a significant proportion of women and farm workers. Our aim was to compare cancer incidence in the cohort (overall, by sex, and by work on farm, occupational status and pesticide use) within the general population.
Methods: More than 180,000 participants in the AGRICAN cohort were matched to cancer registries to identify cancer cases diagnosed from enrolment (2005-2007) to 31st December 2011.
Studies in farmers suggest a possible role of pesticides in the occurrence of Central Nervous System (CNS) tumors but scientific evidence is still insufficient. Using data from the French prospective agricultural cohort AGRICAN (Agriculture & Cancer), we investigated the associations between exposure of farmers and pesticide users to various kinds of crops and animal farming and the incidence of CNS tumors, overall and by subtypes. Over the 2005-2007, 181,842 participants completed the enrollment questionnaire that collected a complete job calendar with lifetime history of farming types.
View Article and Find Full Text PDFAgricultural exposure and risk of bladder cancer in the AGRIculture and CANcer cohort.
Int Arch Occup Environ Health
February 2017
Purpose: Literature on agricultural activities and bladder cancer risk is scarce. However, farmers can be subjected to carcinogenic exposure (e.g.
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