Publications by authors named "Elisabeth M J Dokter"
Article Synopsis
- Preoperative illnesses, particularly mild ones like common colds, were analyzed for their impact on complications after hypospadias surgery in children.
- A study involving 681 boys showed that having a mild illness before surgery was associated with a lower rate of complications post-surgery, with a 50% risk reduction compared to those without illnesses.
- The findings suggest that these common preoperative illnesses do not increase the risk of complications and may even offer some protective effects, indicating that preoperative screening practices do not need to change.
AGORA, a data- and biobank for birth defects and childhood cancer.
Birth Defects Res A Clin Mol Teratol
August 2016
Background: Research regarding the etiology of birth defects and childhood cancer is essential to develop preventive measures, but often requires large study populations. Therefore, we established the AGORA data- and biobank in the Netherlands. In this study, we describe its rationale, design, and ongoing data collection.
View Article and Find Full Text PDFBackground: Hypospadias is a congenital malformation with both environmental factors and genetic predisposition involved in the pathogenesis. The role of maternal periconceptional folic acid supplement use in the development of hypospadias is unclear. As folate levels may also be influenced by the C677T polymorphism in the methylenetetrahydrofolate reductase (MTHFR) gene, we hypothesize that a gene-environment interaction between this polymorphism and folic acid use is involved in the etiology of hypospadias.
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