Publications by authors named "Elisabeth M Hummel"
Biological aging markers in blood and brain tissue indicate age acceleration in alcohol use disorder.
Alcohol Clin Exp Res (Hoboken)
February 2024
Article Synopsis
- Alcohol use disorder (AUD) may lead to accelerated biological aging, which is linked to increased health risks, particularly through inflammation and changes in DNA related to brain function.
- The study examined various biological age markers in brain and blood samples from individuals with and without AUD, revealing significant links between certain markers and accelerated aging specifically in certain brain regions and blood samples.
- Findings indicated that while some age markers suggested accelerated aging in individuals with AUD, others showed no significant relationship, highlighting the complexity of biological aging in substance use disorders.
PTSD is a prevalent mental disorder that results from exposure to extreme and stressful life events and comes at high costs for both the individual and society. Therapeutic treatment presents the best way to deal with PTSD-the mechanisms underlying change after treatment, however, remain poorly understood. While stress and immune associated gene expression changes have been associated with PTSD development, studies investigating treatment effects at the molecular level so far tended to focus on DNA methylation.
View Article and Find Full Text PDF