Publications by authors named "Elisabeth Kjelsvik Steinsvik"

Background: The relationship between gut microbiota and irritable bowel syndrome (IBS) subtype is unclear. We aimed to explore whether differences in fecal bacteria composition and short-chain fatty acid (SCFA) levels were associated with subtypes and symptoms of IBS.

Methods: All participants delivered fecal samples and self-reports on IBS Symptom Severity Score (IBS-SSS), Bristol Stool Scale (BSS), and Gastrointestinal Symptom Rating Scale (GSRS).

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Background: A low FODMAP diet (LFD) is an established dietary treatment for patients with irritable bowel syndrome (IBS). However, knowledge on the extended effects of the restriction phase regarding nutrient intake, symptom severity, and quality of life (QoL) is sparse. Therefore, our objectives were to evaluate the safety of a dietitian-led 12-week strict LFD on measures of blood biochemistry, nutritional status, symptom severity, and QoL.

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: Irritable bowel syndrome (IBS) is a chronic functional gastrointestinal disorder characterized by recurrent abdominal pain associated with alterations  in stool form and/or stool frequency. Co-morbidities such as anxiety, depression, fatigue, and insomnia are frequently reported by patients suffering from IBS. Identification of these symptoms should thus be an integral part of an IBS assessment.

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Article Synopsis
  • Irritable bowel syndrome (IBS) is linked to unexplained gastrointestinal symptoms and involves complex interactions between the brain, gut, and microbiota, prompting a multifaceted study to explore these relationships.
  • The study involves deep phenotyping of 100 IBS patients and 40 healthy controls, utilizing various assessments such as psychometric tests, biological samples, and imaging techniques over a two-year period.
  • A subgroup of IBS patients will undergo a 12-week low FODMAP dietary intervention to assess its impact on symptoms, microbiota, cognitive functions, and brain structure while employing advanced machine learning for analysis and potential biomarker identification.
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