Publications by authors named "Elisabeth Irving"
Article Synopsis
- - Cerebral amyloid angiopathy (CAA) leads to gait impairments, but the relationship between these impairments and brain structure is not well understood.
- - The study assessed participants with CAA, Alzheimer's disease (AD), and normal controls, measuring gait performance along with brain white matter and grey matter characteristics.
- - Findings indicated that reduced white matter integrity and grey matter atrophy are linked to poorer gait performance across all groups, highlighting significant neurological factors that contribute to gait issues in CAA and AD.
Background Gait is a complex task requiring coordinated efforts of multiple brain networks. To date, there is little evidence on whether gait is altered in cerebral amyloid angiopathy (CAA). We aimed to identify impairments in gait performance and associations between gait impairment and neuroimaging markers of CAA, cognition, and falls.
View Article and Find Full Text PDFBackground: Cerebral amyloid angiopathy (CAA) is associated with cognitive decline. CAA has diverse impacts on brain structure and function; however, the brain lesions that mediate the association of CAA with cognition are not understood well.
Aims: To determine the degree to which CAA neuroimaging biomarkers mediate the association of CAA with cognitive dysfunction.