Publications by authors named "Elisabeth Avril"

Article Synopsis
  • - Psychiatric disorders like schizophrenia are prevalent among people who use drugs (PWUD), making medication adherence difficult, especially for those with co-occurring addictions.
  • - A case study from a supervised drug consumption facility in Paris showed that administering penfluridol, a long-acting antipsychotic, helped a patient with schizophrenia and multiple drug dependencies.
  • - Penfluridol not only improved the patient's psychotic symptoms but also enhanced their participation in addiction care and stability in the "Housing First" program, demonstrating its potential role in harm reduction strategies.
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Article Synopsis
  • People who inject drugs (PWID) in Georgia, where hepatitis C virus (HCV) prevalence is high, were studied to assess their adherence to treatment and outcomes.
  • An observational study found that 98% of the 244 participants completed their treatment, and 84.8% achieved sustained virologic response (SVR), with adherence being a key factor in success.
  • The study concludes that with peer support and a simple treatment regimen, PWID can achieve good treatment outcomes, showing that concerns about adherence may be overstated.
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Early onset of heroin use is a severity marker of heroin use disorder. We studied the interaction between early onset and rapid transition to heroin dependence recorded with retrospective interviews in 213 patients with severe heroin dependence and history of methadone maintenance treatment. General linear models were used to identify independent factors associated with early onset, factors associated with rapid transition to dependence, and a multivariate model was used to study the interaction of those two dimensions.

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Background: Drug use and hepatitis C virus (HCV) are both major public health issues in Georgia. However, the access to HCV prevention and care is still very limited in the country. This study was conducted to examine the HCV epidemic among people who inject drugs (PWID) in Tbilisi and to assess the treatment needs of this most-at-risk population.

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