Publications by authors named "Elisabeth A Vandenberghe"
Minimal residual disease negative complete response (MRD-negative CR) provides an early marker for time to treatment failure (TTF) in CLL treated with fludarabine, cyclophosphamide, and rituximab (FCR). MRD was assessed after four FCR cycles (FCR4); MRD-negative CR patients discontinued treatment. Fifty-two patients (35M; 17F) were enrolled.
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- Immune-mediated hemolysis is a significant complication after transplantation, yet mechanisms connecting various cases are often overlooked.
- The study reviewed three patient cases to highlight different types of immune-mediated red blood cell destruction post-transplantation, illustrating complexities such as autoimmune hemolytic anemia and passenger lymphocyte syndrome.
- Proper understanding of the causes of posttransplant immune hemolysis is essential for effective management, especially as doctors see more long-term survivors from unrelated bone marrow and peripheral blood transplants.
We have carried out comparative genomic hybridization (CGH) analysis on archival biopsy material from a series of 30 UK mantle cell lymphomas. The most frequent aberrations were gains of 3q (21 cases), 6p (19 cases), 7q (8 cases), 12p (8 cases), 12q (9 cases) and 17q11q21 (8 cases), and losses of 1p13p32 (10 cases), 5p13p15.3 (9 cases), 6q14q27 (11 cases), 8p (7 cases), 11q13q23 (8 cases) and 13q (18 cases).
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