Prostein expression is highly restricted to normal and malignant prostate tissues.

Background: Prostein is a recently described molecule expressed at the mRNA level in a prostate-specific manner. A murine monoclonal antibody was developed, characterized, and used to evaluate the expression of prostein protein in prostatic, other normal tissue and tumor samples.

Methods: The murine anti-prostein monoclonal antibody 10E3-G4-D3 was generated using recombinant prostein.