Camel Grass Phenolic Compounds: Targeting Inflammation and Neurologically Related Conditions.

Background: The use of plants for therapeutic purposes has been supported by growing scientific evidence.

Methods: This work consisted of (i) characterizing the phenolic compounds present in both aqueous and hydroethanol (1:1, /) extracts of camel grass, by hyphenated liquid chromatographic techniques, (ii) evaluating their anti-inflammatory, antioxidant, and neuromodulation potential, through cell and cell-free models, and (iii) establishing a relationship between the chemical profiles of the extracts and their biological activities.

Results: Several caffeic acid and flavonoid derivatives were determined in both extracts.

Replacing liquid with solid dosage forms in pediatric practice: Feasibility and economic impact from a hospital-based study.

Aim Of The Study: To identify the 10 drugs most frequently administered to children in liquid dosage forms which are eligible for replacement with suitable authorized solid dosage forms and to assess the expected economic impact of this substitution.

Methods: The health record data from 312,152 oral drug administrations were analyzed. Ten drugs were selected according to their frequency of administration in liquid dosage forms, the availability of solid form alternatives, and the suitability of these alternatives for the children receiving the corresponding liquid forms.

Psychological well-being and family satisfaction levels five years after being confirmed as a carrier of the Machado-Joseph disease mutation.

The present study on long-term outcome of presymptomatic testing for Machado-Joseph disease (MJD) aimed to evaluate the psychological well-being and the familial satisfaction of subjects that 5 years prior received an unfavorable result in the predictive testing (PT). The study included 47 testees of Azorean origin (23 from the island of Flores and 24 from S. Miguel) that completed the fourth evaluation session of the MJD protocol, and undertook a neurological examination at the moment of participation in the study.