The Evolution of Physical Performance throughout an Entire Season in Female Football Players.

Research on the evolution of performance throughout a season in team sports is scarce and mainly focused on men's teams. Our aim in this study was to examine the seasonal variations in relevant indices of physical performance in female football players. Twenty-seven female football players were assessed at week 2 of the season (preseason, PS), week 7 (end of preseason, EP), week 24 (half-season, HS), and week 38 (end of season, ES).

Resveratrol Regulates the Expression of Genes Involved in CoQ Synthesis in Liver in Mice Fed with High Fat Diet.

Resveratrol (RSV) is a bioactive natural molecule that induces antioxidant activity and increases protection against oxidative damage. RSV could be used to mitigate damages associated to metabolic diseases and aging. Particularly, RSV regulates different aspects of mitochondrial metabolism.

[Regulation of the expression of coenzyme Q-synthesis complex during ageing].

Introduction: Coenzyme Q is an essential component in the activity of the mitochondrial electron transport chain. Its synthesis involves, at least, a complex of ten different proteins. In this study, an attempt is made to determine the evolution of the expression of the genes involved in coenzyme Q synthesis during mouse ageing.

Organ and tissue-dependent effect of resveratrol and exercise on antioxidant defenses of old mice.

Background: Oxidative stress has been considered one of the causes of aging. For this reason, treatments based on antioxidants or those capable of increasing endogenous antioxidant activity have been taken into consideration to delay aging or age-related disease progression.

Aim: In this paper, we determine if resveratrol and exercise have similar effect on the antioxidant capacity of different organs in old mice.

Physical activity affects plasma coenzyme Q10 levels differently in young and old humans.

Coenzyme Q (Q) is a key lipidic compound for cell bioenergetics and membrane antioxidant activities. It has been shown that also has a central role in the prevention of oxidation of plasma lipoproteins. Q has been associated with the prevention of cholesterol oxidation and several aging-related diseases.

Modulation of endogenous antioxidant activity by resveratrol and exercise in mouse liver is age dependent.

Unlabelled: Aging is a multifactorial process in which oxidative damage plays an important role. Resveratrol (RSV) and exercise delay some of the damages occurring during aging and increase life span and health span. We treated mice at different ages with RSV during 6 months and trained them during the last 6 weeks to determine if RSV and exercise induce changes in endogenous antioxidant activities in liver and if their effects depend on the age of the animal at the beginning of the intervention.

Calorie restriction modifies ubiquinone and COQ transcript levels in mouse tissues.

We studied ubiquinone (Q), Q homologue ratio, and steady-state levels of mCOQ transcripts in tissues from mice fed ad libitum or under calorie restriction. Maximum ubiquinone levels on a protein basis were found in kidney and heart, followed by liver, brain, and skeletal muscle. Liver and skeletal muscle showed the highest Q(9)/Q(10) ratios with significant interindividual variability.