Publications by authors named "Elisa Munoz Gomariz"
Article Synopsis
- The study aimed to analyze gender differences and the impact of time since disease onset in patients with ankylosing spondylitis (AS) using data from the Spanish Registry of spondyloarthritis (REGISPONSER).
- Researchers evaluated various aspects of 1514 AS patients, including demographics, clinical activity, and structural damage through standardized assessments like the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI).
- Results indicated that men had an earlier onset and longer disease duration, while women showed higher BASDAI scores and familial patterns, highlighting significant gender-based clinical implications in AS management.
Objective: To compare the clinical, demographic, and serologic characteristics and the treatment of patients diagnosed with ankylosing spondylitis (AS) from Europe (EU) and Latin America (LA).
Methods: We included 3439 patients from national registries: the Spanish Registry of Spondyloarthritis (REGISPONSER), the Belgian registry (ASPECT), and the Latin American Registry of Spondyloarthropathies (RESPONDIA). We selected patients with diagnosis of AS who met the modified New York classification criteria.
Background: Chronic obstructive pulmonary disease (COPD) exacerbation increases mortality and resources used associated with hospitalization. We studied whether early home monitoring reduces the rate of readmission and if there are any predictor variables.
Patients And Methods: We performed a prospective, controlled, parallel-group study in patients who were hospitalized for COPD.
Aim: Describe gender-based violence by intimate partners against female nurses in a sample of nurses in Andalucia, Spain.
Design: Descriptive transversal study.
Setting: Hospitals and primary health care districts in Andalucia.
Objective: Ankylosing spondylitis (AS) is a chronic inflammatory disease mainly affecting the axial skeleton and characterized by ossification of the spinal disc, joints, and ligaments leading to progressive ankylosis. Vertebral osteoporosis is a recognized feature of AS. Studies have confirmed a moderate to high prevalence of vertebral fractures with extremely varying ranges in patients with AS.
View Article and Find Full Text PDFObjective: To assess clinical variables that may be useful in differentiating gynaecomastia from carcinoma and to analyse the contribution of mammography and ultrasound to the evaluation of male breast disease.
Methods: All men who underwent mammography and/or ultrasound between 1993 and 2006 in our hospital were retrospectively evaluated. Clinical characteristics in patients with gynaecomastia and those with carcinoma were compared.
Calcium-dependent nitric oxide production is involved in the cytoprotective properties of n-acetylcysteine in glycochenodeoxycholic acid-induced cell death in hepatocytes.
Toxicol Appl Pharmacol
January 2010
The intracellular oxidative stress has been involved in bile acid-induced cell death in hepatocytes. Nitric oxide (NO) exerts cytoprotective properties in glycochenodeoxycholic acid (GCDCA)-treated hepatocytes. The study evaluated the involvement of Ca2+ on the regulation of NO synthase (NOS)-3 expression during N-acetylcysteine (NAC) cytoprotection against GCDCA-induced cell death in hepatocytes.
View Article and Find Full Text PDFObjective: To evaluate the efficacy of joint lavage in patients with osteoarthritis of the knee.
Design: We conducted an open prospective study involving 111 patients of whom 77% were females. The patients' age range was 43-81 years and the average age 64±8.
Background: Ageing is associated with changes in the immune system with substantial alterations in T-lymphocyte subsets. Cytomegalovirus (CMV) is one of the factors that affect functionality of T cells and the differentiation and large expansions of CMV pp65-specific T cells have been associated with impaired responses to other immune challenges. Moreover, the presence of clonal expansions of CMV-specific T cells may shrink the available repertoire for other antigens and contribute to the increased incidence of infectious diseases in the elderly.
View Article and Find Full Text PDFObjectives: Although clinicians recognize hip involvement, which frequently leads to hip replacement surgery, as an important feature of AS, data on the epidemiology, nature of the disease and therapeutic strategies are scarce. We aimed to describe the epidemiology of clinical and radiological hip involvement and define the risk factors for the hip replacement surgery in AS patients.
Methods: Data from 3 datasets were merged, including 847 Belgian (ASPECT database), 1405 Spanish (REGISPONSER database) and 466 Ibero-American (RESPONDIA database) AS patients.
Objective: To determine the first signs and symptoms, and the clinical, biological and radiological characteristics of patients with early SpA.
Methods: A total of 150 SpA patients were selected from 2367 listed in REGISPONSER (Registro Español de Espondiloartritis de la Sociedad Española de Reumatología). The inclusion criterion was a disease course of
Unlabelled: The present study evaluated the effect of infliximab on the myeloperoxidase (MPO) concentration in chronic inflammatory joint disease. Eighteen patients were divided into active and inactive groups. Erythrocyte sedimentation rate, C-reactive protein, white blood cell counts, MPO concentration, and biomarkers of oxidative stress were measured before and after the infusion of infliximab.
View Article and Find Full Text PDFObjective: To assess the diagnostic validity, degree of patient satisfaction, and economic cost of home sleep monitoring compared to conventional polysomnography.
Patients And Methods: Consecutive patients with symptoms indicative of sleep apnea-hypopnea syndrome (SAHS) were included. We analyzed the diagnostic yield of home sleep monitoring using the apnea-hypopnea index (AHI), number of desaturations of at least 3%, and the percentage time with arterial oxygen saturation below 90%.
Objectives: To know the perception of Spanish rheumatologists of the profile of the patient with ankylosing spondyloarthritis, candidate for biological therapy treatment. To determine what proportion of patients with ankylosing spondylitis is considered a candidate for this therapy and to know up to what point this decision agrees with the recommendations of the ASAS working group on anti-TNF therapies and with the consensus of the SER METHOD: Rheumatologists from 19 Spanish centers who are experts in treating patients with AS and in the use of anti-TNF drugs participated in this study but they were not aware of the recommendations of the ASAS group and of the SER (unpublished until this work).
Results: One hundred and eighty five patients were included in the study.
Introduction: Tumor necrosis factor (TNF) plays an important role in the pathology of ankylosing spondylitis (AS). Therefore, anti-TNF antibody based therapies could hopefuly be a treatment in AS patients without response to current drugs, mainly non-steroidal antiinflammatory drugs (NSAIDs).
Objective: To assess the evidence from clinical trials on the efficacy of anti-TNF alpha for the treatment of AS by performing a meta-analysis to derive estimates of responses occurring in randomized trials employing anti-TNF therapy.
Objectives: The aims of this study were to assess the efficacy of infliximab (IFX) combined with methotrexate (MTX) versus IFX alone in the treatment of ankylosing spondylitis (AS).
Methods: The study was a 30weeks open label and prospective study of parallel groups in 19 patients with active AS. These patients had shown incomplete therapeutic response to standard therapy (full dose of non-steroidal anti-inflammatory drugs: NSAIDs) and disease modifying antirheumatic drugs: DMARDs (MTX or sulfasalazine: SLZ) for a period of at least 12 weeks and were treated with IFX (5mg/kg).
Objective: The European Spondylarthropathy Study Group (ESSG) criteria for the classification of spondyloarthropathies (SpA) were developed with the aim of unifying and facilitating international medical communication. We assessed the potential of ESSG criteria as a diagnostic aid for rheumatology practices in terms of sex and prevalence rate.
Methods: Data from 2 similarly designed and developed studies conducted in France and Spain were examined.