On the mechanism of marine fouling-prevention performance of oil-containing silicone elastomers.

For many decades, silicone elastomers with oil incorporated have served as fouling-release coating for marine applications. In a comprehensive study involving a series of laboratory-based marine fouling assays and extensive global field studies of up to 2-year duration, we compare polydimethylsiloxane (PDMS) coatings of the same composition loaded with oil via two different methods. One method used a traditional, one-pot pre-cure oil addition approach (o-PDMS) and another method used a newer post-cure infusion approach (i-PDMS).

Addressing the burden of student loan debt: A case-based review of influencing considerations.

Purpose: The following review is offered as an aid for encouraging deeper understanding by pharmacy graduates of approaches to debt management.

Summary: The phenomenon of growing debt for pharmacists and other professionals has been well described. Significant debt is widespread with both pharmacy students and graduates; a recent study described the debt-to-income ratio for pharmacists to have risen by 141% between 2010 and 2016.

Patient self-prescription and antimicrobial stewardship: Considerations for primary care.

Objective: Stewardship efforts within institutions are commonplace, but fewer programs exist in community health care settings. Existing efforts focus on improving appropriate prescribing; however, clinicians must consider the use of antibiotics without a prescription as a contributor to antibiotic resistance. The objective of this article is to report observed methods of antibiotic self-prescription within the United States.

Sexual Dysfunction in a Patient Taking Ledipasvir/Sofosbuvir for the Treatment of Hepatitis C: A Case Report.

Sexual dysfunction is a bothersome side effect of several medications, though it has not yet been reported with the use of ledipasvir/sofosbuvir for the treatment of hepatitis C. However, sexual dysfunction is a potentially unrecognized side effect of ledipasvir/sofosbuvir that could result in nonadherence and treatment failure. We report a case of a 42-year-old man with a sudden onset of sexual dysfunction with the initiation of ledipasvir/sofosbuvir for the treatment of hepatitis C.