Survey on the culture of patient safety among Spanish health care residents.

To improve patient safety, it is essential to have knowledge of the attitudes of all those involved in health care. The Thomas Jefferson Survey on Inpatient Adverse Events was translated and validated; all residents in Asturias, Spain, were invited to complete the survey. A total of 359 residents (60%) completed the survey; 50% of those surveyed agreed that adverse events (AEs) can be prevented.

Evaluation of tolerability and efficacy of imatinib mesylate in elderly patients with chronic phase CML: ELDERGLI study.

Imatinib mesylate (IM) is the treatment of choice in patients with newly diagnosed chronic myeloid leukemia (CML), irrespectively of their age. Nevertheless, information regarding tolerability and responses in advanced-age patients, a subgroup in which co-morbidities and other factors may influence outcome, is scarce, since they were excluded from most clinical trials. In this observational study (ELDERGLI), information regarding demographics, concomitant medication, physical examination, performance status, hemogram, biochemistry, hematologic, cytogenetic and molecular responses, time to progression, adverse events (AE) and severe adverse events (SAE) were prospectively recorded in a series of 36 elderly patients with CML, with a median age of 76.