Publications by authors named "Elisa Fardelli"

Article Synopsis
  • The study focuses on a resilient Gram-negative bacterium that can survive harsh hospital conditions due to its resistance to dehydration.
  • Researchers used μ-Raman spectroscopy and atomic force microscopy (AFM) to assess the bacterium's membrane properties during a 16-week dehydration period, observing that its membranes remained intact despite undergoing structural changes.
  • Findings showed a link between changes in the membrane properties and bacterial fitness, suggesting μ-Raman can effectively evaluate bacterial health status nondestructively and efficiently.
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In the last decades, Mars has been widely studied with on-site missions and observations, showing a planet that could have hosted life in the past. For this reason, the recent and future space missions on the red planet will search for traces of past and, possibly, present life. As a basis for these missions, Space Agencies, such as the European Space Agency, have conducted many experiments on living organisms, studying their behavior in extraterrestrial conditions, learning to recognize their biosignatures with techniques remotely controllable such as Raman spectroscopy.

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Acinetobacter baumanni, is an opportunistic nosocomial multi-drug resistant bacterium, which represents a threat for human health. This pathogen is able to persist in intensive care units thanks to its extraordinary resistance towards dehydration, whose mechanisms are unknown and enable it to easily spread through surfaces, contaminating also medical devices. In this article we reveal, with a multimodal approach, based on μ-R Spectroscopy, Gas Chromatography coupled to Mass Spectroscopy, Atomic Force Microscopy and Fluorescence Recovery After Photobleaching, the bio-physical mechanisms that the membrane of two A.

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