Publications by authors named "Elisa D Vecchia"
Mol Pharmacol
August 2021
Article Synopsis
- * A study identified ebselen, a small molecule, that binds covalently to 14-3-3 proteins, decreasing their stability and disrupting their interaction with partner proteins like Ser19-phosphorylated tyrosine hydroxylase.
- * Ebselen showed promise in lowering 14-3-3 protein levels in cells and zebrafish models, leading to effects similar to lithium, suggesting its potential as a safer alternative for treating conditions related to these proteins.
