Publications by authors named "Elisa Brangi"
Determinants of invasive left atrial pressure in patients with atrial fibrillation.
Eur Heart J Cardiovasc Imaging
October 2024
Article Synopsis
- - This study aims to determine how cardiac structure and function relate to mean left atrial pressure (LAP) in patients with atrial fibrillation (AF), as estimating left ventricular filling pressures can be difficult in these cases.
- - Researchers included 101 patients undergoing transcatheter ablation, measuring invasive LAP during the procedure and echocardiography beforehand; they found that those with increased LAP had lower global longitudinal strain and poorer right ventricular function.
- - Key predictors for elevated LAP included higher E/e' ratio and lower peak atrial longitudinal strain, with the minimum left atrial volume index being the best indicator; these findings offer insight into assessing cardiac filling pressures in AF patients.
The endothelium is a continuous layer of cells that coats the interior walls of arteries, capillaries, and veins. It has an essential regulatory role in hemostatic function, vascular tone, inflammation, and platelet activity. Endothelial dysfunction is characterized by a shift to a proinflammatory and prothrombic state, and it could have a bidirectional relationship with heart failure (HF).
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