Publications by authors named "Elisa Biecher"
ChemistryOpen
August 2024
Article Synopsis
- Research explored the effects of different length disulfide (S-S) linkers on RNA hairpins, specifically using dimethylene (DME), diethylene (DEE), and dipropylene (DPE) linkers.
- Synthesis of modified uridine phosphoramidites allowed for the incorporation of these linkers into RNA sequences, with thermal analysis revealing that DEE and DPE linkers destabilize RNA duplexes while maintaining hairpin structure.
- Results showed that DME and DEE linkers enhance hairpin locking, while DPE offers more conformational flexibility, indicating the utility of S-S linkers in studying RNA interactions.
