Successful outcome of disseminated mucormycosis in a 3-year-old child suffering from acute leukaemia: the role of isavuconazole? A case report.

Background: The use of isavuconazole is approved for the management of invasive aspergillosis and mucormycosis, only in adults, as no paediatric pharmacology studies have been reported to date. Very few paediatric cases have been published concerning the use of isavuconazole. Amphotericin B is the only antifungal agent recommended in paediatric mucormycosis, but adverse effects and especially nephrotoxicity, even with the liposomal formulation, could be problematic.

Assessment of micro-dose biplanar radiography in lower limb measurements in children.

Objectives: To evaluate in children microdose protocol compared with low dose for lower limb alignment (LLA) measurements on biplanar radiography.

Methods: Children 6 years or older were included. Height, weight and hip width were measured prior to imaging.

Traumatic avulsion of the superior extensor retinaculum of the ankle as a cause of subperiosteal haematoma of the distal fibula in children. A retrospective study of 7 cases.

Objective: To describe a new sonographic feature for a traumatic lesion of the ankle in children.

Materials And Methods: We present a retrospective review of superior extensor retinaculum (SER) avulsions diagnosed by ultrasound (US) as a cause of subperiosteal haematoma (SPH) and periosteal apposition of the distal fibula in seven children (3 girls and 4 boys, mean age 13.4 years; age range 10-15 years) after an inversion trauma of the ankle.

Prospective evaluation of free-breathing diffusion-weighted imaging for the detection of inflammatory bowel disease with MR enterography in childhood population.

Objective: To evaluate prospectively the performance of diffusion-weighted imaging (DWI) for the detection of active lesions on MR enterography (MRE) in children with inflammatory bowel disease (IBD).

Methods: MRE of 48 children (mean age 13 years) with suspected or known IBD were blindly analysed by 2 independent readers for the presence of active lesions. Two sets of imaging including DWI and gadolinium-enhanced imaging (GEI) were reviewed.

Diffusion-weighted imaging for the detection of mesenteric small bowel tumours with Magnetic Resonance--enterography.

Purpose: To retrospectively investigate the added value of diffusion-weighted MR imaging (DWI) for detecting mesenteric small bowel tumours (MSBTs) via MR-enterography.

Materials And Methods: MR-enterographies of 98 patients with suspected MSBTs were blindly analyzed by two independent readers for the presence of MSBTs. Four imaging sets including "standard" (Haste and TrueFisp), "standard + DWI," "standard + gadolinium-enhanced" and "standard + DWI + gadolinium-enhanced" were reviewed.

Diagnostic value of diffusion-weighted magnetic resonance imaging in pelvic abscesses.

Objective: The objective of this study was to prospectively assess the added value of gadolinium-enhanced and diffusion-weighted (DWI) magnetic resonance imaging (MRI) to pelvic T2-weighted MRI for diagnosis of deep pelvic abscesses.

Methods: Twenty-nine patients with suspected abscess and a control group of 43 patients underwent T2-weighted, gadolinium-enhanced, T1-weighted and DWI magnetic resonance sequences. Three readers (R1, R2, R3) scored likelihood of abscess on standard MRI, standard MRI + gadolinium, and standard MRI + DWI.

Skeletal involvement in Langerhans cell histiocytosis.

Unlabelled: Langerhans cell histiocytosis (LCH) represents a disorder characterised by an abnormal accumulation of histiocytes in miscellaneous tissues. The bone is commonly affected, especially the flat bones, the spine and the long bones. Some lesions in children such as a "vertebra plana" or a solitary lytic lesion of the skull may be suggestive for LCH, whereas others can be confused with a malignant tumour or osteomyelitis.

Prospective evaluation of magnetic resonance enterography for the detection of mesenteric small bowel tumours.

Purpose: To prospectively evaluate magnetic resonance (MR) enterography for detecting mesenteric small-bowel tumours (MSBTs) and assess the added value of gadolinium-chelate injection.

Material And Methods: Over a 2-year period MR enterography examinations of 75 patients (33 men, 42 women; mean age, 53.8 years; range, 19-85) with suspected MSBT were blindly analysed by two readers for the presence of MSBT.

Effectiveness of MR enterography for the assessment of small-bowel diseases beyond Crohn disease.

The use of cross-sectional imaging techniques for the noninvasive evaluation of small-bowel disorders is increasing. The effectiveness of magnetic resonance (MR) enterography for the evaluation of Crohn disease, in particular, is well described in the literature. In addition, MR enterography has an evolving though less well documented role to play in the evaluation of other small-bowel diseases, including various benign and malignant neoplasms arising in isolation or in polyposis syndromes such as Peutz-Jeghers, inflammatory conditions such as vasculitis and treatment-induced enteritis, infectious processes, celiac disease, diverticular disease, systemic sclerosis, and bowel duplication.

Multimodality imaging of melanoma metastases to the abdomen and pelvis.

Disease in the abdomen and pelvis is frequent in patients with metastatic melanoma (MM). Multidetector row computed tomography is the imaging modality of choice for diagnosis and follow-up of MM. However, positron emission tomographic scan may be used as well as other newer imaging modalities, particularly for imaging of the abdominal and pelvic metastases.