Publications by Elina Kaprio

Publications by authors named "Elina Kaprio"

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Drug-induced pneumonitis risk in diffuse large B-cell/follicular lymphoma patients treated with R-CHOP-like regimen is associated with the use of granulocyte colony-stimulating growth factors.

Elina Kaprio Roosa Prusila Susanna Tokola Milla E L Kuusisto Esa Jantunen

Cancer Med

January 2024

Background: Rituximab-based combinations are the standard of care in diffuse large B-cell lymphoma (DLBCL) and follicular lymphoma (FL). Despite being on market for over 20 years, some of the adverse effects associated with the use of rituximab are not well known. Drug-induced interstitial pneumonitis (DIP) is a potentially fatal complication of the treatment.

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Impact of central nervous system (CNS) prophylaxis on the incidence of CNS relapse in patients with high-risk diffuse large B cell/follicular grade 3B lymphoma.

Hanne Kuitunen Elina Kaprio Peeter Karihtala Ville Makkonen Saila Kauppila

Ann Hematol

August 2020

Article Synopsis

* High-risk patients are recommended to receive CNS prophylaxis, but there is no clear agreement on who qualifies as "high-risk" or the best prophylactic method.
* A study of 95 high-risk DLBCL patients showed that using high-dose methotrexate with R-CHOP significantly reduced CNS relapse rates (5% with prophylaxis vs. 26% without), indicating it may help prevent CNS failures.

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