The abuse of anabolic androgenic steroids (AAS) outside of sports is a far greater societal problem than the abuse in sports. Therefore, there is an increasing need for a suitable clinical method for analysis of AAS in urine samples, but only three clinical laboratories in Sweden currently perform analyses of AAS outside of sports. There is a need for harmonization regarding which substances to be analyzed, which analytes to measure and which concentration thresholds (»cut-offs«) to us.
View Article and Find Full Text PDFAmphetamine is an illicit central nervous system stimulant that is also used for the treatment of attention-decific/hyperacticity disorder (ADHD). Amphetamine exits as two enantiomers, dex(tro)amphetamine (D-amphetamine; also called S-amphetamine) and levoamphetamine (L-amphetamine; or R-amphetamine), of which mainly the former is used as medication for ADHD, whereas illicit street amphetamine is a racemic mixture. To monitor patient compliance with treatment and detect (side) intake of racemic amphetamine, chiral analysis in samples of urine, oral fluid, or blood is used and has traditionally involved reporting of the L/D ratio.
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