A longitudinal study of facial function, quality of life, and depression in Bell's palsy during pregnancy and puerperium.

Bell's palsy can reduce facial function and quality of life. Pregnancy may also be physically and psychologically challenging. This study investigates depression among pregnant and puerperal women with and without Bell's palsy and if degree of facial palsy and depression was correlated.

Sequelae Treatment Needs Following Peripheral Facial Palsy: Retrospective Analysis of 525 Patients.

Objective: This study uses retrospective longitudinal data from a large unselected cohort of patients with peripheral facial paralysis to determine the prevalence and patient characteristic predictors of sequelae receiving intervention.

Study Design: Retrospective case review.

Setting: Karolinska University Hospital in Stockholm Sweden serves as the only tertiary facial palsy center in the region.

Bell's Palsy in Pregnancy and Postpartum: A Retrospective Case-Control Study of 182 Patients.

Objective: To assess the incidence of Bell's palsy in pregnant and postpartum women. Additionally, to compare facial outcomes in terms of Sunnybrook score following Bell's palsy with regard to corticosteroid treatment and other confounding factors.

Study Design: Retrospective case-control study.

Voice rest after vocal fold polyp surgery: A Swedish register study of 588 patients.

Objective: To evaluate the impact of voice rest on patient-reported voice outcome 4 months after vocal fold polyp surgery.

Methods: Preoperative information was collected about age, sex, and smoking habits and the voice handicap index-10 (VHI-10). Four months postoperatively, voice rest (total voice rest, spoke single words, and spoke normally), and pre and postoperative voice therapy were reported.

Complications of Gastrostomy Tubes in Patients With Head and Neck Cancer.

Objectives: Head and neck cancers (HNCs) include various malignant tumors of the upper aerodigestive tract. Due to their anatomical location, HNCs can cause obstruction, odynophagia, or trismus, leading to dysphagia. In addition, this patient group may be vulnerable to treatment side effects both by surgery and oncological treatment, exposing the patients to an even higher risk of malnutrition.

The facial nerve palsy and cortisone evaluation (FACE) study in children: protocol for a randomized, placebo-controlled, multicenter trial, in a Borrelia burgdorferi endemic area.

Background: Children with acute peripheral facial nerve palsy cannot yet be recommended corticosteroid treatment based on evidence. Adults with idiopathic facial nerve palsy are treated with corticosteroids, according to guidelines resulting from a meta-analysis comprising two major randomized placebo-controlled trials. Corresponding trials in children are lacking.

Quality of Life in Bell's Palsy: Correlation with Sunnybrook and House-Brackmann Over Time.

Objectives: To compare patient-graded facial and social/well-being function with physician-graded facial function in Bell's palsy over time.

Study Design: A prospective follow-up study at two tertiary otorhinolaryngological centers.

Methods: A total of 96 patients, 36 women and 60 men, aged 18-77 years, were included.

Gain-of-function mutation of microRNA-140 in human skeletal dysplasia.

MicroRNAs (miRNAs) are post-transcriptional regulators of gene expression. Heterozygous loss-of-function point mutations of miRNA genes are associated with several human congenital disorders, but neomorphic (gain-of-new-function) mutations in miRNAs due to nucleotide substitutions have not been reported. Here we describe a neomorphic seed region mutation in the chondrocyte-specific, super-enhancer-associated MIR140 gene encoding microRNA-140 (miR-140) in a novel autosomal dominant human skeletal dysplasia.

Validation of a Swedish version of the Facial Disability Index (FDI) and the Facial Clinimetric Evaluation (FaCE) scale.

Conclusion: Swedish versions of the Facial Disability Index (FDI) and Facial Clinimetric Evaluation (FaCE) scale are psychometrically valid. Both questionnaires can be used for clinical studies on peripheral facial palsy patients, and provide important information on quality of life.

Objectives: To translate and validate Swedish versions of the FDI and FaCE scale in patients with peripheral facial palsy.

The effect of prednisolone on sequelae in Bell's palsy.

Objective: To study whether prednisolone reduces sequelae in Bell's palsy.

Design: Prospective, randomized, double-blind, placebo-controlled, multicenter trial with 12 months of follow-up.

Setting: Seventeen referral centers.

Prediction of nonrecovery in Bell's palsy using Sunnybrook grading.

Objectives/hypothesis: To develop a clinical prognostic model to identify Bell's palsy patients with risk for nonrecovery at 12 months.

Study Design: Data from a prospective, randomized, double-blind, placebo-controlled, multicenter study.

Methods: There were 829 patients with Bell's palsy randomized in a factorial fashion to treatment with prednisolone or no prednisolone.

Early deterioration in Bell's palsy: prognosis and effect of prednisolone.

Objective: To assess if early deterioration is a negative prognostic factor in Bell's palsy and if prednisolone treatment reduces early progression and enhances recovery.

Study Design: Data extracted from the randomized, double-blind, placebo-controlled multicenter, Scandinavian Bell's palsy study.

Setting: Sixteen tertiary referral centers in Sweden and one in Finland.

The effect of study design and analysis methods on recovery rates in Bell's palsy.

Objectives/hypothesis: We investigated how study design affects the rate of recovery in Bell's palsy.

Study Design: Prospective, randomized, double-blind, placebo-controlled, multicenter trial.

Methods: Data were extracted from the Scandinavian Bell's palsy study, which included 829 patients.