Publications by authors named "Elijah Salzer"
Vacuum-induced tamponade for managing postpartum hemorrhage: a systematic review.
J Matern Fetal Neonatal Med
December 2024
Article Synopsis
- - Postpartum hemorrhage is a significant cause of maternal health issues globally, and a new low-suction vacuum hemorrhage device (VHD) may offer an alternative treatment when standard medications fail.
- - A systematic review analyzed data from six studies, involving a total of 1,018 participants, where VHDs showed around 90% effectiveness in controlling bleeding within 5 minutes and had a total deployment time of 3 hours.
- - Although some minor adverse events were reported, the conclusion suggests that VHDs could provide a fast and effective mechanical solution for postpartum hemorrhage, but further rigorous studies are needed to evaluate their safety and efficacy.
Article Synopsis
- Zuranolone is a new oral medication designed to treat major depressive disorder (MDD) and postpartum depression (PPD), utilizing the neurosteroid allopregnanolone.
- A systematic review and meta-analysis examined the effectiveness of zuranolone, assembling data from 6 studies involving 1,707 participants, all showing low risk of bias.
- Results revealed a significant reduction in depression scores for PPD at 15 days post-treatment, but while there was some improvement for MDD, it was not clinically significant, indicating a need for further research on long-term effects.