Publications by authors named "Elijah Nep"

Context: Global studies on L. (Papaveraceae) traditionally used against malaria in Mali are limited to its low-mass compounds activities, and little information on its bioactive polysaccharides is available.

Objective: This study determines the structure and the immunomodulatory activity of polysaccharides from aerial parts of .

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The goal of this research was to assess the effects of autoclaving followed by freeze-drying on acetylated xerogel (AXS) and carboxymethylated (CMS) derivatives of Plectranthus esculentus starch as potential vaccine stabilizers. Starch extracted from tubers of P. esculentus were modified by single (carboxymethylation) and dual (acetylation followed by xerogel formation) methods.

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This study was aimed at evaluating the physicochemical and rheological properties of starch-based xerogels. The starch from the shoots of Borassus aethiopium was physically modified by xerogelization, and chemically by acetylation, and combination of acetylation and xerogelization. The solubility, swelling and syneresis of the starches were determined by gravimetric techniques.

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Article Synopsis
  • * It was found that balanced forces between the drug particles and the matrix surface allowed for optimal drug release, which was influenced by the type of matrix and the dissolution media used.
  • * The results indicated that softer gels (like E50LV) led to faster drug release compared to stiffer gels (like E10M), based on differences in stress and stiffness measured during the experiments.
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