Publications by authors named "Elif Ozozen Sahin"
Article Synopsis
- The study focused on the serum levels of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) in breast cancer patients to assess their predictive value for treatment response, especially after neoadjuvant chemotherapy.
- A total of 96 breast cancer patients and 35 healthy individuals were evaluated, measuring MMP-2, MMP-9, TIMP-1, and TIMP-2 levels using ELISA.
- Results indicated higher levels of MMP-9 and TIMP-2 in breast cancer patients, which may help gauge tumor stage and chemotherapy response, while MMP-2 levels were lower at diagnosis and correlated negatively with tumor size and metastasis post-treatment.
Secondary bacterial infections in patients with coronavirus disease 2019-associated pneumonia.
Rev Assoc Med Bras (1992)
February 2022
Objective: The vast majority of patients who hospitalized with coronavirus disease 2019 are given empirical antibiotic therapy. However, information on the frequency, microorganism species, and resistance rates of secondary bacterial infections in coronavirus disease 2019 patients are insufficient. We aimed to show the frequency of secondary infections and resistance conditions in patients with coronavirus disease 2019 hospitalized in the intensive care unit.
View Article and Find Full Text PDFBackground: The aim of this study was to determine the in vitro efficacy of intravenous (IV) fosfomycin against extensively drug-resistant Enterobacterales strains and the effect of glucose 6-phosphate (G6-P) on sensitivity results.
Material Method: Thirty-two extensively drug-resistant Klebsiella pneumonia strains were included in the study. Detection of the carbapenemase genes was performed using the Gene-Xpert® System Carba R® kit.