Evaluation of oxidative stress responses and neurotoxicity potential of diazinon in different tissues of Cyprinus carpio.

Toxicity of organophosphorus insecticides is mainly due to the inhibition of acetylcholinesterase, but, oxidative stress may be involved in the toxicity of this pesticides. Therefore, it was investigated whether diazinon, a commonly used organophosphate, may induce oxidative stress and cholinesterase inhibition in different tissues of Cyprinus carpio. Sublethal concentrations of diazinon (0.

Effects of diazinon on acetylcholinesterase activity and lipid peroxidation in the brain of Oreochromis niloticus.

The aim of this study was to investigate the effects of organophosphorus (OP) pesticide diazinon on acetylcholinesterase (AChE: EC 3.1.1.

Marker enzyme assessment in the liver of cyprinus carpio (L.) exposed to 2,4-D and azinphosmethyl.

The potential utility of antioxidant enzymes and lipid peroxidation as indicators of exposure to 2,4-D and azinphosmethyl together with the toxic effects of these compounds in freshwater fish Cyprinus carpio were evaluated. Biochemical parameters were recorded spectrophotometrically in fish liver, which were exposed to a single dose of 2,4-D and azinphosmehtyl (1/3 LC(50)), and their mixture at 1:1 ratio for 24, 48, 72, and 96 h. The most sensitive parameter was glutathione S-transferase (GST) activity, which significantly increased with experimental exposures.