Evaluation of S100A12 protein levels in children with familial Mediterranean fever.

Background/aim: Familial Mediterranean fever (FMF), the most common autoinflammatory disease in children, is characterized by recurrent febrile episodes. FMF is known to progress with chronic inflammation, particularly during attack periods. This study aimed to investigate the relationship of S100A12, an inflammatory marker, with attacks and inflammatory events in FMF patients.

The role of endothelium-derived hyperpolarizing factor in children with familial mediterranean fever.

Objective: Familial Mediterranean Fever is an autoinflammatory disease characterized by inflammatory attacks in serous tissues often accompanied by endothelial dysfunction. This study aimed to evaluate the effect of endothelium-derived hyperpolarizing factor, which is an indicator of endothelial dysfunction in children with familial Mediterranean fever.

Methods: This study include 57 children with familial Mediterranean fever and 31 children as healthy controls.

Nasal nitric oxide levels in primary ciliary dyskinesia, cystic fibrosis and healthy children.

Güney E, Emiralioğlu N, Cinel G, Yalçın E, Doğru D, Kiper N, Özçelik HU. Nasal nitric oxide levels in primary ciliary dyskinesia, cystic fibrosis and healthy children. Turk J Pediatr 2019; 61: 20-25.

An evaluation of thiol/disulphide homeostasis in patients with psoriasis.

Introduction: The role of oxidative stress in the pathogenesis of psoriasis has been investigated in previous studies with conflicting results. On the other hand, well-established treatments currently used in psoriasis exert their effects via a boost of oxidative stress. Recently, a strong positive association between psoriasis, metabolic syndrome and dyslipidemia has also been described showing the complex nature of the disease.