Ibrexafungerp: A narrative overview.

Ibrexafungerp (IBX) is a new antifungal drug that recently entered the antifungal landscape. It disrupts fungal cell wall synthesis by non-competitive inhibition of the β-(1,3)-D-glucan (BDG) synthase enzyme. It has demonstrated activity against a range of pathogens including and spp.

An Overview of 10 Years of Activity of a Molecular Laboratory for Buruli Ulcer Diagnosis at a Field Hospital in Benin.

Buruli ulcer (BU) is a neglected tropical disease caused by Mycobacterium ulcerans. Early diagnosis is crucial to prevent morbidity. In November 2012, a field laboratory fully equipped for the rapid on-site quantitative PCR (qPCR) diagnosis of M.

Importance of consultations using mobile teams in the screening and treatment of neglected tropical skin diseases in Benin.

Context: Since 2013, the World Health Organization has recommended integrated control strategies for neglected tropical diseases (NTDs) with skin manifestations. We evaluated the implementation of an integrated approach to the early detection and rapid treatment of skin NTDs based on mobile clinics in the Ouémé and Plateau areas of Benin.

Methods: This descriptive cross-sectional study was performed in Ouémé and Plateau in Benin from 2018 to 2020.

Never seen right gastrothorax: A case report.

Traumatic gastrothorax, or stomach herniation into the chest post-trauma, is a rare but dangerous condition that can lead to respiratory distress and obstructive shock. Its diagnosis is challenging and requires a high index of suspicion. Immediate stomach decompression is an important, often life-saving step of the treatment, prior to definitive surgical repair.

[Sleep quality is a determinant of hip bone mineral density in a group of young Lebanese men].

Introduction: The aim of this study was to explore the relationship between sleep quality and bone mineral density (BMD) of the hip in a group of young Lebanese men.

Methods And Results: Fourteen Lebanese young men from 18 to 30 years (mean age 22.6 years) participated in this study.

Aerobic training suppresses exercise-induced lipid peroxidation and inflammation in overweight/obese adolescent girls.

This study aimed to determine whether aerobic training could reduce lipid peroxidation and inflammation at rest and after maximal exhaustive exercise in overweight/obese adolescent girls. Thirty-nine adolescent girls (14-19 years old) were classified as nonobese or overweight/obese and then randomly assigned to either the nontrained or trained group (12-week multivariate aerobic training program). Measurements at the beginning of the experiment and at 3 months consisted of body composition, aerobic fitness (VO2peak) and the following blood assays: pre- and postexercise lipid peroxidation (15F2a-isoprostanes [F2-Isop], lipid hydroperoxide [ROOH], oxidized LDL [ox-LDL]) and inflammation (myeloperoxidase [MPO]) markers.

Bone mineral content and density in obese, overweight and normal weight adolescent boys.

Aim Of The Study: The aim of this study was to compare bone mineral content (BMC), bone mineral density (BMD) and bone mineral apparent density (BMAD) in obese, overweight and normal weight adolescent boys.

Methods & Results: This study included 23 obese, 19 overweight and 25 normal weight adolescents (aged 14-20 years) boys. The three groups (obese, overweight and normal weight) were matched for age and maturation index.

Geometric indices of hip bone strength in obese, overweight, and normal-weight adolescent girls.

The aim of this study was to compare hip bone strength indices in obese, overweight, and normal-weight adolescent girls using hip structure analysis (HSA). This study included 64 postmenarcheal adolescent girls (14 obese, 21 overweight, and 29 normal weight). The 3 groups (obese, overweight, and normal weight) were matched for maturity (years since menarche).

Influence of the weight status on hip bone strength indices in a group of sedentary adolescent girls.

Objective: The aim of this study was to compare femoral shaft and intertrochanteric geometry in overweight and normal weight adolescent girls.

Methods And Results: This study included 22 overweight (Body mass index (BMI) > 25 kg/m2) adolescent girls (15.4 +/- 2.

Bone mass in a group of Lebanese girls from Beirut and French girls from Orleans.

Aim Of The Study: To compare bone mineral content (BMC) and bone mineral density (BMD) in a group of Lebanese girls from Beirut and French girls from Orléans.

Methods: This study included 26 French adolescent girls (153 +/- 0.7 years old) and 24 maturation-matched (15.

[Influence of being overweight on bone mineral apparent density in a group of Lebanese adolescent girls].

Aim Of The Study: To explore the effects of being overweight on lumbar spine (L2-L4) and femoral neck (FN) bone mineral apparent density (BMAD) in a group of Lebanese adolescent girls.

Methods And Results: Forty-two Lebanese postmenarchal adolescent girls participated in this study (22 overweight [BMI > 25 kg/m2] adolescent girls [15.4 +/- 2.

Hip bone strength indices in overweight and control adolescent boys.

The influence of being overweight on bone strength in adolescents remains controversial. The aim of this study was to compare hip bone strength indices in overweight and control adolescent boys using hip structure analysis (HSA). This study included 25 overweight adolescent boys [body mass index (BMI) >25 kg/m(2)] and 31 maturation-matched controls (BMI <25 kg/m(2)).

Relative importance of lean mass and fat mass on bone mineral density in a group of Lebanese postmenopausal women.

The aim of this study was to determine the relative importance of lean mass and fat mass on bone mineral density (BMD) in a group of Lebanese postmenopausal women. One hundred ten Lebanese postmenopausal women (aged 65-84 yr) participated in this study. Age and years since menopause were recorded.

Bone mineral content and density in overweight and control adolescent boys.

The aim of this study was to compare bone mineral content (BMC) and areal bone mineral density (aBMD) in overweight and control adolescent boys. This study included 27 overweight (body mass index [BMI] > 25 kg/m²) adolescent (17.1 ± 2.

Birth weight a negative determinant of whole body bone mineral apparent density in a group of adolescent boys.

The aim of this study was to explore the relation between birth weight and bone mass in a group of adolescent boys. This study included 44 adolescent (aged 14-20yr) boys. Anthropometric characteristics (height and weight) were measured and birth weights were obtained from the obstetric records.

Influence of age and morphological characteristics on whole body, lumbar spine, femoral neck and 1/3 radius bone mineral apparent density in a group of Lebanese adolescent boys.

The purpose of this study was to analyse the relationships between age, morphological characteristics (weight, height, body mass index (BMI), fat and lean mass), daily calcium intake (DCI), physical activity and bone mineral apparent density (BMAD) of the whole body (WB), lumbar spine (L2-L4), femoral neck (FN) and 1/3 radius in a group of Lebanese adolescent boys. This study included 60 Lebanese adolescent (16.8 ± 2.

Bone mineral content and density in obese, overweight, and normal-weighted sedentary adolescent girls.

Purpose: The aim of this study was to compare the whole body (WB) bone mineral content (BMC) and bone mineral density (BMD) in obese, overweight, and normal-weighted adolescent sedentary girls.

Methods: This study included 17 obese, 27 overweight, and 21 normal-weighted adolescent (aged, 12-20) sedentary (practicing less than 2 hours of physical activity/week) girls. The three groups (obese, overweight, and normal) were matched for age and maturation index (years since menarche).

Anaerobic and aerobic energy system contribution to 400-m flat and 400-m hurdles track running.

The present study was designed to determine the aerobic and anaerobic energy contributions to 400-m Flat (400 mF) and 400-m hurdles (400 mH) using the accumulated oxygen deficit method. Six nationally ranked athletes, specializing in 400 mH and familiar with 400 mF volunteered to participate in this study. All the participants performed 3 track-running sessions.

Catecholamine response to exercise in obese, overweight, and lean adolescent boys.

Introduction: The aim of this study was to examine the effect of body fat percentage on the plasma catecholamine response to a cycling sprint test (CST) in sedentary adolescent boys.

Methods: In this study, 31 adolescent boys (9 obese (% body fat = 31.0% ± 3.

Body mass index and body fat in Lebanese female adolescents.

Objective: The aim of this study is to investigate the relation between body mass index (BMI) and body fat (BF) among Lebanese female adolescents.

Methods: 51 Lebanese females aged 12 to 18 years participated in this study. BMI was calculated as weight/height.

Femoral neck geometry in overweight and normal weight adolescent girls.

Being overweight is associated with increased bone mineral content, bone mineral density (BMD), and bone strength in adults. However, the effect of being overweight on bone strength during adolescence is poorly understood. The aim of this study was to compare femoral neck geometry in overweight and normal weight adolescent girls.