Blood eosinophils, specific immunoglobulin E, and bronchiolitis severity.

Background: Bronchiolitis is the leading cause of hospitalization for United States infants. Blood eosinophil and serum specific IgE (sIgE) levels are separately linked to clinical severity but few studies have examined these biomarkers together.

Objective: Among infants hospitalized for bronchiolitis, we investigated the association between (1) blood eosinophilia and severity, (2) sIgE sensitization and severity, and (3) interaction between the two biomarkers on severity.

Socioeconomic Status and Bronchiolitis Severity Among Hospitalized Infants.

Objective: To investigate the relationship between socioeconomic factors and bronchiolitis severity among hospitalized infants.

Methods: We performed a 17-center, prospective cohort study from 2011 to 2014. Children <1 year old hospitalized with bronchiolitis were enrolled.