Publications by authors named "Elias Uyar"

Article Synopsis
  • An 84-year-old woman with a past medical history of hypertension, diabetes, and hypothyroidism presented with a rapidly growing thigh mass, which was diagnosed as high-grade leiomyosarcoma that doubled in size within two weeks.
  • Following surgery and initiation of radiotherapy, she developed complications including respiratory distress and heart failure due to extensive metastatic disease and a pulmonary embolism.
  • The case emphasizes the difficulties in treating aggressive sarcomas in frail patients and suggests that earlier intervention with chemotherapy might have led to better outcomes, highlighting the importance of careful patient evaluation for cancer treatment options.
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Sickle cell disease (SCD) is a hereditary hemoglobinopathy that can lead to progressive vasculopathy, increasing the risk of cerebrovascular complications. Moyamoya syndrome (MMS), a rare disorder characterized by stenosis of the internal carotid arteries, can occur in SCD patients due to chronic endothelial damage and inflammation. The coexistence of these conditions can result in severe cerebrovascular complications, presenting unique diagnostic and therapeutic challenges.

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We present a 45-year-old African American male with a medical history of advanced-stage HIV/AIDS (CD4 count: 1 cell/μL) and poor adherence to highly active antiretroviral therapy (HAART), who presented with symptoms of diarrhea, weakness, and respiratory distress. Upon admission, duodenal and colonic biopsies revealed a diffuse histiocytic infiltrate consistent with complex (MAC), and a cecal biopsy was positive for Kaposi sarcoma (KS). Further workup showed consolidation and a right pleural effusion on chest X-ray, suggesting a pneumonia infection.

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