Bias and precision of SPECT-based Lu activity-concentration estimation using a ring-configured solid-state versus a dual-headed anger system.

Background: The aim was to compare bias and precision for Lu-SPECT activity-concentration estimation using a dual-headed Anger SPECT system and a ring-configured CZT SPECT system. This was investigated for imaging at 208 keV and 113 keV, respectively.

Methods: Phantom experiments were performed on a GE Discovery 670 system with 5/8'' NaI(Tl) crystal (dual-headed Anger system) and a GE StarGuide (ring-configured CZT system).