Publications by authors named "Elias Karsten"

Purpose: Financial toxicity arises in cancer patients from subjective financial distress due to objective financial burden from the disease or treatment. Financial toxicity associates with worse outcomes. It has not been described in cancer patients undergoing radiotherapy in Germany and its publicly funded health system.

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Introduction: Artefacts caused by dental implants and hip replacements may impede target volume definition and dose calculation accuracy. The iterative metal artefact reduction (iMAR) algorithm can provide a solution for this problem. The present study compares delineation of gross tumour volumes (GTVs) and organs at risk (OARs) in the pelvic and the head and neck (H & N) regions using computed tomography (CT) with and without iMAR, and thus the practical applicability of iMAR for routine clinical use.

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Article Synopsis
  • - The study aimed to automate the delineation of organs at risk (OARs) in treatment planning using the Brainlab Anatomical Mapping tool for auto-segmentation of CT data.
  • - A retrospective evaluation of 24 patient datasets assessed the accuracy of the auto-segmentation compared to traditional manual delineation, with strong results for most OARs indicated by high Dice similarity coefficients.
  • - The findings suggest that the Brainlab software is clinically viable for many OARs, while recommending improvements in the study design for future research.
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