Publications by authors named "Elias Daud"

Article Synopsis
  • Time-resolved 3D cine phase-contrast cardiovascular magnetic resonance (4D flow CMR) is a method used to analyze blood flow, but it can be affected by various confounders like field strength and scanner configurations.
  • This study involved 19 healthy volunteers who underwent 4D flow CMR at four different sites, with measurements taken from the thoracic aorta and the entire heart to assess the impact of these confounding factors.
  • Results indicated that while some parameters showed good inter-site reproducibility (e.g., in the ascending aorta), others had significant discrepancies, particularly at Site IV, highlighting the need for standardization in 4D flow CMR measurements.
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Article Synopsis
  • The study examines two commercially available software for analyzing three-dimensional flow in cardiovascular MRI, focusing on how they affect key metrics like forward flow volume (FFV), peak velocity (PV), and wall shear stress (WSS).
  • Data was collected from MRI scans of 30 participants (healthy volunteers and patients with aortic issues) to assess the software's performance in different analysis planes.
  • Overall, the two software packages showed good correlation for FFV and PV, particularly in healthy individuals, but displayed poor agreement for WSS analysis, highlighting variability in results based on the software used.
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Cardiac hypertrophy develops following different triggers of pressure or volume overload. In several previous studies, different hypertrophy types were demonstrated following alterations in extracellular signal-regulated kinase (ERK) pathway activation. In the current study, we studied two types of cardiac hypertrophy models in rats: eccentric and concentric hypertrophy.

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Background: The availability of advanced technologies for mechanical support in hospitals with on-site cardiac surgery (CS), along with the ability to perform urgent coronary artery bypass graft (CABG) surgery, may result in improved clinical outcomes in patients with acute coronary syndrome (ACS).

Methods: We conducted a retrospective analysis of the bi-annually Acute Coronary Syndrome Israeli Survey (ACSIS) registry from the year 2000 to 2020, performed in hospitals with and without CS. Mortality rates and major adverse cardiac and cerebrovascular events (MACCE) rates are reported.

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Background: Parametric mapping sequences in cardiovascular magnetic resonance (CMR) allow for non-invasive myocardial tissue characterization. However quantitative myocardial mapping is still limited by the need for local reference values. Confounders, such as field strength, vendors and sequences, make intersite comparisons challenging.

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Background: Myocardial fibrosis is a multistep process, which results in collagen deposition in the injured muscle. Empagliflozin, a sodium-glucose cotransporter 2 inhibitor (SGLT2i), decreases cardiovascular events risk. Little is known on the effects of empagliflozin in non-diabetic patients early post myocardial infarction.

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Background: A sinus of Valsalva aneurysm (SVA) is a rare cardiac anomaly. Most SVA's rupture into right heart chambers and can be classified using the modified Sakakibara classification according to the site of rupture. Transoesophageal echocardiography (TOE) is a useful diagnostic tool and aides in treatment planning in patients with congenital anomalies in emergency situations.

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