Publications by authors named "Eliane Wurdig Roesch"
This study aimed to develop and validate a rapid method for identification by MALDI-TOF system and determination of the susceptibility to Fluconazole and Micafungin by broth microdilution among Candidaspecies causing bloodstream infections. Subcultures from blood culture bottles were incubated for 5 hours (+/- 1h) and used to perform the tests, so that the turnaround time of rapid identification and susceptibility profile was about 5 and 24 hours, respectively. The rapid identification showed agreement of 92.
View Article and Find Full Text PDFObjectives: To analyze the clinical characteristics and outcomes of admitted patients with the hospital- versus community-manifested COVID-19 and to evaluate the risk factors related to mortality in the first population.
Methods: This retrospective cohort included consecutive adult patients with COVID-19, hospitalized between March and September 2020. The demographic data, clinical characteristics, and outcomes were extracted from medical records.
Rapid bacterial identification by MALDI-TOF MS directly from blood cultures and rapid susceptibility testing: A simple approach to reduce the turnaround time of blood cultures.
Braz J Infect Dis
February 2023
Article Synopsis
- - Antimicrobial treatment for bloodstream infections (BSI) is urgent due to rising antimicrobial resistance, making quick identification and testing of bacteria crucial for effective therapy.
- - This study evaluates a rapid method utilizing MALDI-TOF MS to identify and assess susceptibility of Gram-negative bacteria directly from blood cultures, achieving high accuracy rates (93% species identification, 100% for rapid susceptibility, and 96% for polymyxin B testing).
- - The protocol demonstrated effectiveness in a routine microbiology lab, particularly for identifying carbapenemase-producing bacteria, offering rapid, simple, and cost-effective diagnosis and treatment options.
Previous studies that assessed risk factors for venous thromboembolism (VTE) in COVID-19 patients have shown inconsistent results. Our aim was to investigate VTE predictors by both logistic regression (LR) and machine learning (ML) approaches, due to their potential complementarity. This cohort study of a large Brazilian COVID-19 Registry included 4120 COVID-19 adult patients from 16 hospitals.
View Article and Find Full Text PDFBackground: It is not clear whether previous thyroid diseases influence the course and outcomes of COVID-19.
Methods: The study is a part of a multicentric cohort of patients with confirmed COVID-19 diagnosis from 37 hospitals. Matching for age, sex, number of comorbidities, and hospital was performed for the paired analysis.
Determination of the susceptibility profile of isolates of from blood culture bottles is extremely important for correctly guiding patient pharmacotherapy. The aim of this study was to compare the results of analysis of isolated directly from blood culture bottles by the VITEK MS MALDI-TOF identification system and the fluconazole disk diffusion assay with those of standard identification methods. Testing directly from the bottle allowed results 24 to 48 hours quicker than the standard method.
View Article and Find Full Text PDFWe evaluated the use of a chromogenic selective medium (MRSA ID) as a useful tool for the detection of methicillin-resistant Staphylococcus aureus (MRSA) in cystic fibrosis (CF) patient samples. Fifty-four MRSA isolates were detected by MRSA ID, while only 24/54 (44%) (odds ratio [OR], 2.79; 95% confidence interval [CI], 1.
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