Publications by authors named "Eliane Naomi Sakane"
Treatment options in hypoparathyroidism.
Arch Endocrinol Metab
November 2022
Hypoparathyroidism remains the single endocrine deficiency disease that is not habitually treated with the missing hormone. In this article, we aim to provide a review of the conventional approach and the novel therapies as well as an overview of the perspectives on the treatment of this rare condition. We conducted a literature review on the conventional therapy using vitamin D analogs and calcium salts, indications for thiazide diuretics and phosphorus binders, PTH analogs history and usage, and the drugs that are currently being tested in clinical trials.
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- The study investigates serum concentrations of 25 hydroxyvitamin D in individuals aged 80 and older in Sao Paulo, Brazil, assessing their relationship with musculoskeletal health and physical performance.
- Among the 212 participants, 56% were found to have vitamin D deficiency, with 13% experiencing severe deficiency, highlighting a significant public health concern.
- Positive associations were noted between higher vitamin D levels and better bone mineral density as well as improved physical performance, while older age and osteoporosis were negatively linked to vitamin D levels.
Background And Objective: Non-communicable diseases like systemic arterial hypertension (SAH) and dyslipidemia are poorly studied in terms of patient journey aspects. This semi-systematic review provides evidence synthesis for the management of SAH and dyslipidemia in Brazil and also discusses challenges faced by patients at the local level along with a suggested care approach by local experts.
Methods: A semi-systematic review using both structured literature databases (Embase and Medline) and unstructured scientific records (WHO, IPD, MOH and Google) on hypertension and dyslipidemia in the English language from 2010 to 2019 was performed by reviewers.
Article Synopsis
- - Osteoporosis is a common condition affecting the bones in postmenopausal women, and the study investigates the effectiveness of Radiofrequency Echographic Multi Spectrometry (REMS) technology for diagnosing it compared to the standard dual X-ray absorptiometry (DXA).
- - The research involved 343 Brazilian women aged 30 to 80 who were evaluated using both REMS and DXA scans to assess how accurately REMS can diagnose osteoporosis.
- - Results indicated that REMS had high diagnostic accuracy, showing no discrepancies between REMS and DXA diagnoses when a 0.3 tolerance on T-score was accepted, suggesting REMS could be a viable option for osteoporosis diagnosis in areas lacking DXA facilities.
Context: The effects of PTH deprivation on bone are still unclear. Our objective was to report the characteristics of patients with postsurgical hypoparathyroidism (PsH) at a specialized outpatient service and correlate their trabecular bone score (TBS) values to clinical, densitometric, and laboratory findings. A secondary objective was to evaluate the fracture rates and look for associations between these events and the collected data.
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