Publications by authors named "Elia Ragot"
Article Synopsis
- The formation of functional organs relies on effective communication between different cell types, and issues in this communication can lead to developmental defects.
- This study uses the Drosophila leg model to identify key proteins that mediate interactions between tendon and muscle precursor cells, highlighting the roles of Amalgam (Ama) and Neurotactin (Nrt).
- Results show that Ama promotes myoblast survival and proliferation independently of Nrt, and both are essential for proper tendon and muscle cell association during development.
Adherent-invasive Escherichia coli (AIEC) were investigated for their involvement in the induction/chronicity of intestinal inflammation in Crohn's disease (CD). AIEC gut establishment is favoured by overexpression of the glycoprotein CEACAM6 in the ileal epithelium. We generated a transgenic mouse model, named 'Vill-hCC6', in which the human CEACAM6 gene was under the control of the villin promoter, conditioning expression in the small intestine.
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