Multi-Server Multi-Function Distributed Computation.

The work here studies the communication cost for a multi-server multi-task distributed computation framework, as well as for a broad class of functions and data statistics. Considering the framework where a user seeks the computation of multiple complex (conceivably non-linear) tasks from a set of distributed servers, we establish the communication cost upper bounds for a variety of data statistics, function classes, and data placements across the servers. To do so, we proceed to apply, for the first time here, Körner's characteristic graph approach-which is known to capture the structural properties of data and functions-to the promising framework of multi-server multi-task distributed computing.

Enterococcus-related vascular graft infection: A case series.

Objectives: We aimed to assess the frequency, management, and burden of enterococcal-related vascular graft infection.

Patients And Methods: From 2008 to 2021, data regarding all episodes of vascular graft infections initially managed or secondarily referred to our referral center were prospectively collected. We described the history and management of the infection, depending on the type of prosthesis used.

Dalbavancin as suppressive therapy for implant-related infections: a case series with therapeutic drug monitoring and review of the literature.

Implant-related infections may need suppressive antibiotic therapy (SAT). We describe a SAT strategy using dalbavancin with therapeutic drug monitoring (TDM). This is a retrospective bicentric study of patients with implant-related infection who received dalbavancin SAT between January 2021 and September 2023.

Burden of Candida-related vascular graft infection: a nested-case control study.

Purpose: We aimed to assess risk factors of candida-related Vascular Graft Infections (VGIs).

Methods: We did a case-control study (1:4) matched by age and year of infection, nested in a cohort of patient with a history of VGIs. Cases were defined by a positive culture for Candida spp.

Genetic variation and genetic complexity of nodule occupancy in soybean inoculated with USDA110 and USDA123 rhizobium strains.

Background: Symbiotic nitrogen fixation differs among Bradyrhizobium japonicum strains. Soybean inoculated with USDA123 has a lower yield than strains known to have high nitrogen fixation efficiency, such as USDA110. In the main soybean-producing area in the Midwest of the United States, USDA123 has a high nodule incidence in field-grown soybean and is competitive but inefficient in nitrogen fixation.

The impact of preoperative nutritional screening, ERAS protocol, and mini-invasive surgery in surgical oncology: A multi-institutional SEM analysis of patients with digestive cancer.

Background: Mini-invasive surgery (MIS), ERAS, and preoperative nutritional screening are currently used to reduce complications and the length of hospital stay (LOS); however, inter-variable correlations have seldom been explored. This research aimed to define inter-variable correlations in a large series of patients with gastrointestinal cancer and their impact on outcomes.

Methods: Patients with consecutive cancer who underwent radical gastrointestinal surgery between 2019 and 2020 were analyzed.

Synthesis of 7-Aminocoumarins from 7-Hydroxycoumarins via Amide Smiles Rearrangement.

N-Substituted 7-aminocoumarins can be synthesized from readily available 7-hydroxycoumarins via alkylation with α-bromoacetamides and subsequent tandem O → N Smiles rearrangement-amide hydrolysis. The key rearrangement sequence proceeds under mild conditions to provide convenient access to various -alkyl and -aryl products in moderate to high yields. The process is operationally simple, inexpensive, transition-metal-free, and can be telescoped into a one-pot process.

The Genome of the Acid Soil-Adapted Strain OR191 Encodes Determinants for Effective Symbiotic Interaction With Both an Inverted Repeat Lacking Clade and a Phaseoloid Legume Host.

Although forms highly effective symbioses with the comparatively acid-sensitive genus , its introduction into acid soils appears to have selected for symbiotic interactions with acid-tolerant strains. has the unusual ability of being able to nodulate and fix nitrogen, albeit sub-optimally, not only with but also with the promiscuous host . Here we describe the genome of OR191 and genomic features important for the symbiotic interaction with both of these hosts.

Preserving US microbe collections sparks future discoveries.

Collections of micro-organisms are a crucial element of life science research infrastructure but are vulnerable to loss and damage caused by natural or man-made disasters, the untimely death or retirement of personnel, or the loss of research funding. Preservation of biological collections has risen in priority due to a new appreciation for discoveries linked to preserved specimens, emerging hurdles to international collecting and decreased funding for new collecting. While many historic collections have been lost, several have been preserved, some with dramatic rescue stories.

Genetic Diversity and Phylogenetic Relationships of Annual and Perennial Species.

We have estimated the average genetic diversity of two annual and six perennial species based upon 76 orthologous gene sets and performed phylogenetic analysis, divergence analysis and tests for departure from neutrality of the eight species using 52 orthologous gene sets. In addition, 367 orthologous gene sets were used to estimate the relationships of 11 accessions. Among the perennials, showed the highest nucleotide diversity.

A Proteomic Network for Symbiotic Nitrogen Fixation Efficiency in Bradyrhizobium elkanii.

Rhizobia colonize legumes and reduce N to NH in root nodules. The current model is that symbiotic rhizobia bacteroids avoid assimilating this NH. Instead, host legume cells form glutamine from NH, and the nitrogen is returned to the bacteroid as dicarboxylates, peptides, and amino acids.

High-quality draft genome sequence of Mlalz-1, a microsymbiont of (L.) miller collected in Lanzarote, Canary Islands, Spain.

10.1601/nm.1335 Mlalz-1 (INSDC = ATZD00000000) is an aerobic, motile, Gram-negative, non-spore-forming rod that was isolated from an effective nitrogen-fixing nodule of (L.

Bomb swab: Can trace explosive particle sampling and detection be improved?

The marked increase in international terror in recent years requires the development of highly efficient methods to detect trace amounts of explosives at airports, border crossings and check points. The preferred analytical method worldwide is the ion mobility spectrometry (IMS) that is capable of detecting most explosives at the nano-gram level. Sample collection for the IMS analysis is based on swabbing of a passenger's belongings to collect possible explosive residues.

Biogeography of a Novel Ensifer meliloti Clade Associated with the Australian Legume Trigonella suavissima.

Here, we describe a novel clade within and consider how geographic and ecological isolation contributed to the limited distribution of this group. Members of the genus are best known for their ability to form nitrogen-fixing symbioses with forage legumes of three related genera, L., Mill.

High-quality permanent draft genome sequence of the type strain USDA 76, isolated from (L.) Merr.

USDA 76 (INSCD = ARAG00000000), the type strain for , is an aerobic, motile, Gram-negative, non-spore-forming rod that was isolated from an effective nitrogen-fixing root nodule of (L. Merr) grown in the USA. Because of its significance as a microsymbiont of this economically important legume, USDA 76 was selected as part of the DOE Joint Genome Institute 2010 sequencing project.

Toxicity assessment of (99m)technetium-labeled human beta-defensin-3 in CD1 mice.

Objective: Human beta-defensin-3 (HBD-3) is an antimicrobial peptide which is up-regulated during inflammation. Based on the previously demonstrated capacity of technetium-99m ((99m)Tc) labelled HBD-3 of distinguishing infection from inflammation in rats, we have decided to collect information on the potential toxicity of the tracer in view of its possible use for imaging in humans.

Materials And Methods: Recombinant HBD-3 underwent labeling with (99m)Tc.

Spontaneous penetration of gold nanoparticles through the blood brain barrier (BBB).

Background: The blood brain barrier (BBB) controls the brain microenvironment and limits penetration of the central nervous system (CNS) by chemicals, thus creating an obstacle to many medical imaging and treatment procedures. Research efforts to identify viable routes of BBB penetration have focused on structures such as micelles, polymeric nanoparticles and liposomes as drug carriers, however, many of them failed to provide unequivocal proof of BBB penetration. Here we proved that gold nanoparticles (AuNPs) penetrate the BBB in rats to reach brain regions.

A new score to predict post operative complications after endovascular treatment of thoraco abdominal aortic aneurysms.

Background: The endovascular treatment of thoraco abdominal aortic aneurysms (TAAA) is a minimally invasive solution. However, patient selection remains a major problem. We have analysed our experience to identify the risk factors for post-operative morbidity and mortality and to construct a scoring system to identify those patients likely to benefit from this treatment.

The role of innate immunity receptors in the pathogenesis of inflammatory bowel disease.

Innate immunity constitutes the first line of defense, fundamental for the recognition and the initiation of an inflammatory response against microorganisms. The innate immune response relies on the sensing of microbial-associated molecular patterns through specialized structures such as toll-like receptors (TLRs) and the nucleotide oligomerization domain- (NOD-) like receptors (NLRs). In the gut, these tasks are performed by the epithelial barrier and the presence of adaptive and innate immune mechanisms.

Effect of external magnetic field on IV 99mTc-labeled aminosilane-coated iron oxide nanoparticles: demonstration in a rat model: special report.

Among the most interesting applications of ferromagnetic nanoparticles (NPs) in medicine is the potential for localizing pharmacologically or radioactively tagged agents directly to selected tissues selected by an adjustable external magnetic field. This concept is demonstrated by the application external magnetic field on IV Tc-labeled aminosilane-coated iron oxide NPs in a rat model. In a model comparing a rat with a 0.

Green synthesis of gold nanoparticles using plant extracts as reducing agents.

Gold nanoparticles (GNPs) were prepared using four different plant extracts as reducing and stabilizing agents. The extracts were obtained from the following plants: Salvia officinalis, Lippia citriodora, Pelargonium graveolens and Punica granatum. The size distributions of the GNPs were measured using three different methods: dynamic light scattering, nanoparticle-tracking analysis and analysis of scanning electron microscopy images.

Tolerability of High Doses of Daptomycin in the Treatment of Prosthetic Vascular Graft Infection: A Retrospective Study.

Introduction: In treatment of prosthetic vascular graft infection (PVGI), appropriate antimicrobial treatment is crucial for controlling the septic process and preventing re-infection of the new graft. Glycopeptides are the mainstay of treatment for device-related infections by methicillin-resistant Staphylococcus aureus strains, but with some limitations, especially concerning vancomycin-intermediate and glycopeptide-intermediate S. aureus.

Intra-abdominal aortic graft infection: prognostic factors associated with in-hospital mortality.

Background: Mortality associated with aortic graft infection is considerable. The gold standard for surgical treatment remains explantation of the graft. However, prognostic factors associated with early mortality due to this surgical procedure are not well-known.

MTHFR polymorphisms C677T and A1298C and associations with IVF outcomes in Brazilian women.

The aim of this study was to investigate the association between MTHFR gene polymorphisms and IVF outcomes in Brazilian women undergoing assisted reproduction treatment. A prospective study was conducted in the Human Reproduction Department at the ABC University School of Medicine and the Ideia Fertility Institute between December 2010 and April 2012. The patient population was 82 women undergoing assisted reproduction cycles.