Publications by authors named "Elia A Eshak"
Article Synopsis
- Previous research shows that tumor processes like angiogenesis and metastasis are influenced by the blood coagulation system, particularly tissue factor (TF), which also affects cell signaling related to cancer progression.
- In a study involving 40 neuroblastoma tissue samples, 75% showed positive TF expression, with a significant correlation between TF levels and the MYCN gene's upregulation, indicating a potential link between these factors.
- TF expression was found to be a significant predictor of patient outcomes, with 60% of patients with positive TF expression dying from the disease, suggesting that TF might be a valuable prognostic marker and a target for future treatments in neuroblastoma.
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