Publications by authors named "Eli Oldham"

Objective: To evaluate data sharing statement (DSS) inclusion within rheumatology clinical studies published over the past four years in ten top rheumatology journals.

Methods: We conducted a systematic review of rheumatology clinical studies published in ten leading journals between January 1, 2020, and December 31, 2023. Articles were included if they provided new primary data through original research and excluded if no new primary data was found.

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Background: Orthopaedic surgery is a critical field, impacting global health-care expenditure and patient outcomes. Despite substantial research funding, issues of transparency and reproducibility persist, undermining the credibility of published in-print findings. Data-sharing initiatives aim to address these challenges by promoting accessibility and enhancing research reliability.

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Background: Emergency medicine remains as the front line of healthcare, providing acute care to a diverse population during urgent and critical moments. Our objective was to systematically quantify the prevalence of data sharing statements (DSS) in high-impact emergency medicine journals and assess their implementation by contacting corresponding authors who indicated data available upon request.

Methods: We conducted a cross-sectional analysis to identify the prevalence and content of data sharing statements in clinical studies published in high impact emergency medicine journals between 2018 and 2023, followed by a hierarchical logistic regression analysis to identify variables impacting the incorporation of data sharing statements into emergency medicine studies.

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We present a rare case of rhabdoid squamous cell carcinoma (RSCC) on the scalp of a non-immunosuppressed male patient in his late 60s. This aggressive variant of squamous cell carcinoma (SCC) is characterized by tumor cells with eccentrically located nuclei and abundant eosinophilic cytoplasm, as observed on histopathological examination. While rhabdoid morphology has been reported in various anatomical sites, its occurrence in primary cutaneous tumors is exceptionally uncommon, with fewer than 10 cases documented to date.

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We report a challenging case of a man in his mid-70s diagnosed with a myxofibrosarcoma-like spindle cell squamous cell carcinoma (ML-SCC) on the scalp. This rare tumor shares cytologic features with spindle cell squamous cell carcinoma (SCC) with myxoid characteristics but also exhibits architectural elements typical of myxofibrosarcoma, making it nearly indistinguishable by routine light microscopic evaluation. Myxoid spindle cell carcinomas are exceptionally rare, and only one case of ML-SCC has been previously documented in the peer-reviewed medical literature.

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Article Synopsis
  • Thrombotic hemangioma with organizing/anastomosing features (THOA) is a newly recognized variant of hemangioma linked to mutations in GNA genes, displaying unique clinical and morphological traits.
  • Although it shows benign behavior, histological features may cause concerns for a low-grade malignant vascular neoplasm.
  • A case study of a 74-year-old woman revealed persistent THOA through next-generation sequencing, identifying specific gene mutations and contributing to understanding the lesion's characteristics and prognosis.
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Schwannomas (SCHs) are benign neural tumors originating from Schwann cells of the peripheral nerve sheaths. These neoplasms typically exhibit hyalinized vessels with impaired vascular permeability; however, angioma-like features are rare. We report an intriguing case of a cutaneous SCH with unusual vascular changes in a 60-year-old female who presented with a tender nodular lesion on her lower back.

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Cutaneous granular cell tumors (GCTs) are rare tumors that typically exhibit benign clinical behavior and are likely of Schwann cell origin. Some histologic and immunohistochemical variants of GCTs may present challenges due to infiltrative growth patterns, perineural invasion, and expression of Melan-A. In this case report, we present a 27-year-old male who had previously been diagnosed with a typical GCT on the back a few years ago.

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