Publications by authors named "Eli Brasowski"
Article Synopsis
- Arginine and its metabolites, crucial for kidney function, may influence the early kidney changes seen in diabetes, but their transport regulation in diabetic kidneys hasn't been explored.
- Researchers examined how arginine was taken up in kidney cells from both diabetic and control rats, alongside other experimental groups to understand these changes.
- Findings revealed that diabetic rats had significantly higher arginine transport due to increased expression of the CAT-1 transporter, suggesting this mechanism contributes to kidney hyperfiltration in diabetes, potentially influenced by nitric oxide production.
