Publications by authors named "Eli Benuck"
Article Synopsis
- The immune system is made up of various cell types that are found in blood and tissues, but research mostly focuses on blood samples, leaving gaps in our understanding of immune variation throughout the body and across different ages.
- Researchers analyzed RNA and surface protein expression from over 1.25 million immune cells collected from various tissues of 24 organ donors aged 20-75 years to understand these variations better.
- They discovered that immune cell composition and function varies significantly based on tissue type and age, providing insights into how immune responses can be linked to disease across the human lifespan.
DNA packaging within chromatin depends on histone chaperones and remodelers that form and position nucleosomes. Cells express multiple such chromatin regulators with overlapping in-vitro activities. Defining specific in-vivo activities requires monitoring histone dynamics during regulator depletion, which has been technically challenging.
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