Front Endocrinol (Lausanne)
May 2021
Obesity is an ever growing pandemic and a prevalent problem among men of reproductive age that can both cause and exacerbate male-factor infertility by means of endocrine abnormalities, associated comorbidities, and direct effects on the precision and throughput of spermatogenesis. Robust epidemiologic, clinical, genetic, epigenetic, and preclinical data support these findings. Clinical studies on the impact of medically induced weight loss on serum testosterone concentrations and spermatogenesis is promising but may show differential and unsustainable results.
View Article and Find Full Text PDFThe aim of the present study was to determine the prevalence of human leukocyte antigen HLA-B27 in Moroccan healthy controls and in patients with ankylosing spondylitis (AS), and to analyze the correlation between HLA-B27 and AS in Moroccan patients. The prevalence of HLA-B27 was determined by evaluating the number of HLA-B27-positive samples in 128 healthy subjects and in 53 patients diagnosed with AS according to the ESSG and AMOR criteria. HLA-B27 was determined by the polymerase chain reaction using sequence-specific primers.
View Article and Find Full Text PDFAlcohol is a well known teratogen. Its role in causing fetal alcohol syndrome/fetal alcohol effects is well documented. A vast amount of study over the past several decades has finally provided insight into many aspects of its effect.
View Article and Find Full Text PDFJ S C Med Assoc
October 1995
Domestic violence is a serious public health problem. The "epidemic" is becoming too obvious to hide, too widespread to deny, and too much of a health hazard to ignore. The victims are children, women, the elderly, and the society as a whole.
View Article and Find Full Text PDFArch Pediatr Adolesc Med
August 1994
Neonates are exposed to a growing list of potentially toxic environmental and therapeutic agents. Such exposure may be through mishap, misjudgment in both drug dosage and route of administration, inadvertent misuse of medications, or improper baby care. In addition, the newborn infant may show signs of adverse reactions to a variety of drugs that are given to the mother and cross the placenta, thereby affecting the fetus before or during both labor and delivery.
View Article and Find Full Text PDFThe umbilical cord is the lifeline of the fetus and of the neonate in the first few minutes after birth. Care of the cord and stump in the immediate neonatal period varies according to social, cultural, economic, and geographic factors. Measures taken to insure sterility in cutting, tying, and painting the umbilical cord may prevent serious diseases such as tetanus neonatorum.
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