Publications by authors named "Elham S H Awad"
Article Synopsis
- The fungal extracts from Drechslera rostrata and Eurotium tonpholium demonstrated strong anti-leishmanial effects against Leishmania major, with IC50 values around 28 μg/mL.
- Seven compounds were isolated and identified from these fungi using various spectroscopic methods, with two compounds (di-2-ethylhexyl phthalate and 1,8-dihydroxy-3-methoxy-6-methyl-anthraquinone) showing notable anti-leishmanial activity at lower IC50 values.
- Oral administration of the extracts and active compounds led to faster healing compared to the traditional drug Pentostam, and no adverse effects on liver or kidney functions were observed in treated animals.
