Kleine-Levin syndrome (KLS) is a rare sleep disorder characterized by periodic hypersomnia and various degrees of cognitive and behavioral disturbance, hyperphagia, and hypersexuality. Effective treatment is challenging. Stimulants marginally address sleepiness, but may increase irritability and do not improve cognitive and behavioral disturbances.
View Article and Find Full Text PDFElectrical dipoles oriented perpendicular to the cortical surface are the primary source of the scalp EEGs and MEGs. Thus, in particular, gyri and sulci structures on the cortical surface have a definite possibility to influence the EEGs and MEGs. This was examined by comparing the spatial power spectral density (PSD) of the upper portion of the human cortex in MRI slices to that of simulated scalp EEGs and MEGs.
View Article and Find Full Text PDFOur objective was to examine if the high-density, 256 channel, scalp interictal EEG data can be used for localizing the epilepsy areas in patients. This was done by examining the long-range temporal correlations (LRTC) of EEGs and also that of the phase synchronization index (SI) of EEGs. It was found that the LRTC of scalp SI plots were better in localizing the seizure areas as compared with the LRTC of EEGs alone.
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