Process optimization and modeling of Pb(II) ions adsorption on chitosan-conjugated magnetite nano-biocomposite using response surface methodology.

This study aimed to investigate the performance of a magnetic nano-biocomposite, chitosan conjugated magnetite nanoparticle (CH-MNP), for the removal of lead ions. The magnetite nanoparticles were synthesized through a controlled co-precipitation technique and were stabilized with citric acid. Subsequently, they were covalently bonded to chitosan via carbodiimide chemistry using EDAC/NHS activation.

Cationic albumin-conjugated magnetite nanoparticles, novel candidate for hyperthermia cancer therapy.

We developed a novel hyperthermia material for cancer therapy, cationic albumin-conjugated magnetite nanoparticles (MNPs), which absorb the energy of an alternating magnetic field and convert it into heat. MNPs of about 10 nm were synthesised through co-precipitation, and citric acid was used to stabilise the MNP suspension. Then albumin was cationised by replacing anionic side chain groups with cationic groups.