Chitosan propolis nanocomposite alone or in combination with apramycin: an alternative therapy for multidrug-resistant in rabbits: and study.

The emergence of multidrug-resistant strains has increased the need for safe, alternative therapies from natural sources with antibacterial properties. There are no published data regarding the use of chitosan propolis nanocomposite (CPNP) either alone or in combination with antibiotics as antimicrobials against , especially in Egypt. This study evaluated the antibacterial activities of five antimicrobials [apramycin, propolis, chitosan nanoparticles (CNPs), chitosan propolis nanocomposite (CPNP) and CPNP +apramycin] against ten virulent and multidrug-resistant (MDR) field strains recovered from diarrheic rabbits through and study.