Association of Prior Antithrombotic Drug Use with 90-Day Mortality After Intracerebral Hemorrhage.

Purpose: To estimate the strength of association between use of antithrombotics (AT) drugs with survival after spontaneous intracerebral hemorrhage (s-ICH) comparing oral anticoagulant (OAC) or platelet antiaggregants (PA) with no AT use and in active comparator analyses OAC vs PA, direct oral anticoagulant (DOAC) vs vitamin K antagonist (VKA), and clopidogrel vs aspirin.

Patients And Methods: We identified patients ≥55 years with a first-ever s-ICH between 2015 and 2018 in Southern Denmark (population 1.2 million).

How the IHR (2005) Shaped the COVID-19 Pandemic Response in the Eastern Mediterranean Region: What Went Well and What Did Not.

The COVID-19 pandemic has underscored the importance of the International Health Regulations (IHR) (2005) in addressing global health emergencies. This review aims to improve healthcare system capabilities, future preparedness, and actions in the Eastern Mediterranean Region, particularly in low-resource areas. The IHR, established in 1969, initially focused on 6 diseases but has since expanded to include a wider range of public health threats.

Depth of Invasion Threshold for Recommending Elective Neck Dissection in T1 or T2 Oral Squamous Cell Carcinoma.

Background: There is variability in the literature on the role of the depth of invasion (DOI) for recommending an elective neck dissection (END).

Purpose: The purpose of the study is to estimate the DOI threshold for recommending an END.

Study Design, Setting, Sample: A retrospective cohort study was performed at McGill University Health Centre from 2008 to 2018 with 5 years of follow-up.

Learning interventions in the WHO Eastern Mediterranean region: supporting Member States to get prepared for better response to health emergencies in the region.

Background: The Eastern Mediterranean Region (EMR) faces numerous public health risks caused by biological, chemical, man-made, and natural hazards. This manuscript aimed to assess the multifaceted interventions and strategies used to strengthen the EMR's preparedness capacities to respond properly to current and upcoming health emergencies.

Objective: To address these challenges, it is crucial to implement comprehensive and robust strategic risk assessments and health emergency preparedness frameworks.

AI-integrated Screening to Replace Double Reading of Mammograms: A Population-wide Accuracy and Feasibility Study.

Mammography screening supported by deep learning-based artificial intelligence (AI) solutions can potentially reduce workload without compromising breast cancer detection accuracy, but the site of deployment in the workflow might be crucial. This retrospective study compared three simulated AI-integrated screening scenarios with standard double reading with arbitration in a sample of 249 402 mammograms from a representative screening population. A commercial AI system replaced the first reader (scenario 1: integrated AI), the second reader (scenario 2: integrated AI), or both readers for triaging of low- and high-risk cases (scenario 3: integrated AI).

Artificial intelligence for MRI stroke detection: a systematic review and meta-analysis.

Objectives: This systematic review and meta-analysis aimed to assess the stroke detection performance of artificial intelligence (AI) in magnetic resonance imaging (MRI), and additionally to identify reporting insufficiencies.

Methods: PRISMA guidelines were followed. MEDLINE, Embase, Cochrane Central, and IEEE Xplore were searched for studies utilising MRI and AI for stroke detection.

Association of Antithrombotic Drug Use With Incident Intracerebral Hemorrhage Location.

Background And Objectives: Few population-based studies have assessed associations between the use of antithrombotic (platelet antiaggregant or anticoagulant) drugs and location-specific risks of spontaneous intracerebral hemorrhage (s-ICH). In this study, we estimated associations between antithrombotic drug use and the risk of lobar vs nonlobar incident s-ICH.

Methods: Using Danish nationwide registries, we identified cases in the Southern Denmark Region of first-ever s-ICH in patients aged 50 years or older between 2009 and 2018.

Breast cancer detection accuracy of AI in an entire screening population: a retrospective, multicentre study.

Background: Artificial intelligence (AI) systems are proposed as a replacement of the first reader in double reading within mammography screening. We aimed to assess cancer detection accuracy of an AI system in a Danish screening population.

Methods: We retrieved a consecutive screening cohort from the Region of Southern Denmark including all participating women between Aug 4, 2014, and August 15, 2018.

Population-wide evaluation of artificial intelligence and radiologist assessment of screening mammograms.

Objectives: To validate an AI system for standalone breast cancer detection on an entire screening population in comparison to first-reading breast radiologists.

Materials And Methods: All mammography screenings performed between August 4, 2014, and August 15, 2018, in the Region of Southern Denmark with follow-up within 24 months were eligible. Screenings were assessed as normal or abnormal by breast radiologists through double reading with arbitration.

Great cardiac vein injury after circumflex artery intervention: a case report.

Background: Injury of the great cardiac vein (GCV) during circumflex coronary artery intervention is not discussed enough in the literature. In addition, relationship between the GCV and circumflex artery is highly variable and practically unpredictable in 30% of cases. This report describes a rare case of GCV injury during circumflex artery intervention.

The role of endosonography in cardiology: case series and literature review.

Aims: Endosonography (EUS) is the diagnostic tool with the highest resolution for the local staging of gastrointestinal tumours and, due to the detailed visualization of the wall layers, is recommended in current guidelines for cancer management. In addition, an endoscope has an ultrasound tip design and balloon insufflation control design, and a 120° bending mechanism to deflect the endoscope tip. These advantages could be beneficial and valuable while investigating the cardiovascular structures during routine gastrointestinal procedures using this diagnostic tool.

Major Cardiovascular Events After Spontaneous Intracerebral Hemorrhage by Hematoma Location.

Importance: Survivors of spontaneous (ie, nontraumatic and with no known structural cause) intracerebral hemorrhage (ICH) have an increased risk of major cardiovascular events (MACEs), including recurrent ICH, ischemic stroke (IS), and myocardial infarction (MI). Only limited data are available from large, unselected population studies assessing the risk of MACEs according to index hematoma location.

Objective: To examine the risk of MACEs (ie, the composite of ICH, IS, spontaneous intracranial extra-axial hemorrhage, MI, systemic embolism, or vascular death) after ICH based on ICH location (lobar vs nonlobar).

Choice of Assessment and Subsequent Risk of Breast Cancer among Women with False-Positive Mammography Screening.

Women with false-positive mammography screening results have a two- to four-fold higher risk of breast cancer. This study aimed to investigate if the subsequent risk of breast cancer after a false-positive mammography screening is associated with the received diagnostic assessment. The study population consisted of women who underwent false-positive mammography screening from January 2010 to June 2019.

Association Between Statin Use and Intracerebral Hemorrhage Location: A Nested Case-Control Registry Study.

Background And Objectives: A causal relationship between statin use and intracerebral hemorrhage (ICH) is uncertain. We hypothesized that an association between long-term statin exposure and ICH risk might vary for different ICH locations.

Methods: We conducted this analysis using linked Danish nationwide registries.

Temperature and Aging Effects on the Rheological Properties and Performance of Geopolymer-Modified Asphalt Binder and Mixtures.

Using geopolymer as a modifier for asphalt binders and mixtures gained momentum for investigation in recent decades. Limited research investigations attempted to link the effect of temperature and traffic loading on the rheological properties and performance of geopolymer-modified asphalt binders. The primary objective of this study is to evaluate the effect of fly ash-based geopolymer (GF), styrene-butadiene-styrene (SBS), and the combination of GF with SBS on the rheological properties and performance of asphalt binders at low and intermediate temperatures.

Incorporation of the Multi-Layer Plastic Packaging in the Asphalt Binders: Physical, Thermal, Rheological, and Storage Properties Evaluation.

The amount of residual Multi-layer Plastic Packaging (MPP) in Canada has greatly increased in the last two decades, which has economic and environmental consequences. MPP is primarily made up of two or more layers of Polyethylene (PE), Polyester (PET), Nylon (NY), and Metalized Polyester (METPET). While MPP has not been used as an asphalt modifier, some of the materials commonly found in MPP, such as PE and PET, have also been successfully used as asphalt modifiers.

Using a Fibrinolysis Delivery Catheter in Pulmonary Embolism Treatment for Measurement of Pulmonary Artery Hemodynamics.

Background: Ultrasound-facilitated and catheter-directed low-dose fibrinolysis (EKOS) has shown favorable hemodynamic and safety outcomes in intermediate- to high-risk pulmonary embolism (PE) cases. Objectives: This prospective single-arm monocentric study assessed the effects of using a delivery catheter for fibrinolysis as a novel approach for acute intermediate- to high-risk patients on pulmonary artery hemodynamics PE. Methods: Forty-five patients (41 intermediate−high and 4 high risk) with computer tomography (CT)-confirmed PE underwent EKOS therapy.

Prostate cancer metastasis mimicking appendicitis-A rare but important differential diagnosis in PET/CT imaging.

Prostate cancer most commonly metastasizes to lymph nodes, bones, the liver, and the lungs. Prostate cancer carcinomatosis with an affinity for the appendix is not well described in current literature and is usually reported with acute appendicitis as the primary presentation. A 65-year-old male with a history of recurrent prostate cancer presented with an increase in PSA value.

Rutting Behaviour of Geopolymer and Styrene Butadiene Styrene-Modified Asphalt Binder.

Modifying asphalt binders is an effective method of improving the performance of asphalt pavement, such as its resistance to rutting. However, because modification changes the behaviour of binders, substantial laboratory testing is required before field application to determine the best mixtures. This research aimed to evaluate the impacts of temperature, stresses, polymer type, and modification rate on the rutting behaviour of the asphalt binder modified with fly-ash-based geopolymer (GF), styrene butadiene styrene (SBS), and a combination of SBS and GF.

Epidemiology of the first and second waves of COVID-19 pandemic in Djibouti and the vaccination strategy developed for the response.

Since the first case of COVID-19 in Djibouti in March 2020 up to the end of May 2021, the country experienced two major epidemic waves of confirmed cases and deaths. The first wave in 2020 progressed more slowly in Djibouti compared with other countries in the Eastern Mediterranean Region. The second wave in 2021 appeared to be more aggressive in terms of the number and severity of cases, as well as the overall fatality rate.

US Survey of Incidence of and Reasons for Nurse Anesthetists Leaving or Having Considered Leaving Their Jobs.

Many nurse anesthetists changing positions or considering leaving their positions can give the impression that suboptimal quality of anesthesia department leadership exists. To provide nationally accurate benchmark data on annual turnovers of nurse anesthetists to assist chief nurse anesthetists who may be scrutinized for the resignation rate of nurse anesthetists at their hospital, we used the 2018 US National Sample Survey of Registered Nurses. Analyses show that, during 2017, approximately 13.

Gastrointestinal stromal tumor with maxillary metastasis: a case report and literature review.

Gastrointestinal stromal tumors (GISTs) form commonly in the stomach, small intestine, colorectum, and esophagus. Metastatic GIST occurs in up to 50% of patients at presentation. The liver and peritoneal cavity are the most common (93%) metastatic sites; head and neck metastases are extremely rare.

COVID-19 pandemic in Djibouti: Epidemiology and the response strategy followed to contain the virus during the first two months, 17 March to 16 May 2020.

First cases of COVID-19 were reported from Wuhan, China, in December 2019, and it progressed rapidly. On 30 January, WHO declared the new disease as a PHEIC, then as a Pandemic on 11 March. By mid-March, the virus spread widely; Djibouti was not spared and was hit by the pandemic with the first case detected on 17 March.