Publications by authors named "Eleuter Samky"

Objective: To evaluate the impact of implementing continuous quality improvement (CQI) methods on patient's experiences and satisfaction in Tanzania.

Design: Cluster-randomized trial, which randomly allocated district-level hospitals into treatment group and control group, was conducted.

Setting: Sixteen district-level hospitals in Kilimanjaro and Manyara regions of Tanzania.

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Article Synopsis
  • The study analyzed HIV-1 incidence and related risk factors in a cohort of adults from Mbeya, Tanzania, to inform efforts to reduce HIV infections while awaiting an effective vaccine.
  • Out of 2578 participants, the overall HIV-1 incidence was 1.35 per 100 person-years, with notably higher rates in females and semiurban males aged 30-34.
  • Key risk factors for HIV-1 acquisition included being female, younger age at enrollment, frequent alcohol use, lower education levels, and having multiple sexual partners, indicating a need for targeted interventions in these groups.
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Objectives: To define and discuss reference ranges for commonly determined laboratory parameters in healthy adults from southern Tanzania.

Methods: A population-based sample of adult volunteers from Mbeya, Tanzania, who were not HIV positive or showing signs and symptoms of other diseases, participated in this study. We enrolled 145 women and 156 men between 19 and 48 years of age to determine clinical chemistry (CC), haematology and lymphocyte immunophenotyping (LIP) parameters using standard laboratory methods.

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Background: Pilot studies suggest that a single, 2-g oral dose of azithromycin may be an alternative to a 2.4-MU intramuscular dose of penicillin G benzathine in the prevention and treatment of syphilis. We evaluated the efficacy of treatment with azithromycin in a developing country.

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Objective: To characterize HIV-1 strains in a potential vaccine trial cohort (CODE) in the Mbeya region of southwest Tanzania.

Design: Study volunteers (n = 3096) were recruited from urban areas in Mbeya Town, using two different recruitment strategies, and in a nearby rural village.

Methods: Cryopreserved plasma from 507 HIV-1 prevalent cases was the source of viral RNA for HIV-1 genotyping by the Multi-region Hybridization Assay, the MHA(acd), and selected strains were confirmed by complete genome sequencing.

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HIV-1 is endemic in Tanzania where three different subtypes, A, C, and D, have been identified. Information on HIV-1 genetic diversity is crucial to define requirements for an effective vaccine, in regions where HIV-1 vaccine trials are planned. To define the subtype distribution of HIV-1 in the Mbeya region of southwest Tanzania, peripheral blood mononuclear cells (PBMC) and plasma were obtained from 36 discarded HIV seropositive blood units.

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