Publications by authors named "Elephtherios Vairaktaris"
Article Synopsis
- Recent approaches for treating oral squamous cell carcinomas (SCC) emphasize the effectiveness of preoperative treatment combining radiation and chemotherapy (neoadjuvant) compared to post-surgery treatments (adjuvant).
- A study of 128 patients found that those receiving neoadjuvant treatment had higher 5-year tumor-free survival rates (e.g., 83% for T1 tumors) than those receiving adjuvant treatment, especially for T1, T2, and T4 tumors.
- Overall, results suggest that neoadjuvant treatment not only improves long-term survival rates but also shows promising outcomes, as 72% of neoadjuvant patients survived the observation period compared to 65
Background And Purpose: In recent years, different concepts for the treatment of oral squamous cell carcinomas (OSCC) have been developed; these include preoperative simultaneous neoadjuvant radiochemotherapy and one-stage surgery with tumor ablation and reconstruction. When considering long-term survival, there is substantial evidence that multimodality treatment based on a neoadjuvant radiochemotherapy is superior to adjuvant therapy concepts based on a surgical approach with postoperative irradiation. The aim of this study was to discuss the 5-year survival rate in a neoadjuvant and an adjuvant combination treatment in patients with primary OSCC.
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